Figure 3 Kaplan-Meier curve analysis and hazard ratios (HRs) for cardiovascular (CV) mortality in patients with acute coronary syndrome (ACS) and a combination of diabetes mellitus (DM), or chronic kidney disease (CKD), or advanced age during the 3-year follow-up period. (A) Kaplan-Meier curve analysis for CV mortality between the ACS population with DM, CKD, or advanced age, or the combination of 2 or 3 risk factors (log-rank P<0.001). (B) In patients with 1 risk factor (DM, CKD, or advanced age), HR of CV mortality was 1.19 (95% CI: 1.00–1.42; P=0.057), 4.43 (95% CI: 3.88–5.05; P<0.001), and 4.47 (95% CI: 3.84–5.21; P<0.001), respectively. In patients with combination of two risk factors, HR of CV mortality was 4.53 (95% CI: 3.74–5.49; P<0.001) for advanced age plus DM, 8.76 (95% CI: 7.76–9.89; P<0.001) for CKD plus advanced age, and 4.17 (95% CI: 3.66–4.74; P<0.001) for CKD plus DM. In elderly patients with DM and CKD, HR of CV mortality was 7.29 (95% CI: 6.42–8.29; P<0.001) during the 3-year follow-up period.