06 March 2024>: Clinical Research
Molecular Determinants of Drug Resistance and Mutation Patterns in Influenza Viruses Circulating in Poland Across Multiple Epidemic Seasons: Implications for Vaccination Strategies
Ewelina Hallmann 1ABDEFG* , Aleksander Masny 1AD , Anna Poznańska 2CD , Francisco Pozo 34A , Inmaculada Casas 34A , Lidia Bernadeta Brydak 1ADDOI: 10.12659/MSM.942125
Med Sci Monit 2024; 30:e942125
Figure 4 An example of a mutation site related to antibody-binding properties: the K369N mutation in the neuraminidase gene of virus A/Brisbane/02/2018 (A/H1N1/pdm09) in clinical sample number 770. The location of the mutation (red) corresponds to position 369 on the viral N chain (yellow backbone) and is 5 Ångström (A) from the heavy chain (H) antibodies (purple skeleton) (created using the FluSurver mutations app – https://gisaid.org/database-features/flusurver-mutations-app/).