Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mechanical Allodynia in a Rat Model of Mild Traumatic Brain Injury

Jiyoun Lee; Soeun Jeon; Nara Kim; Sangmin Choi; Wangseok Do; Jae-Rin Kim; Eunsoo Kim; Jeong-Min Hong; Jiseok Baik

doi:10.12659/MSM.942574

01 February 2024 : Animal Research

Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mechanical Allodynia in a Rat Model of Mild Traumatic Brain Injury

Jiyoun Lee

^1BCDEF, Soeun Jeon

^2ABCDE, Nara Kim

^3BE, Sangmin Choi

^3BE, Wangseok Do

^3ABC, Jae-Rin Kim

^4BCE, Eunsoo Kim

^34AC, Jeong-Min Hong

^34AC, Jiseok Baik

^34ACDEFG*

DOI: 10.12659/MSM.942574

Med Sci Monit 2024; 30:e942574

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Figure 1 Flow chart of the studyGroup S – sham surgery; Group T – traumatic brain injury; Group K – intrathecal ketamine group; POD – postoperative day; BDNF – brain-derived neurotrophic factor.

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Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mechanical Allodynia in a Rat Model of Mild Traumatic Brain Injury

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