01 February 2024 : Animal Research
Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mechanical Allodynia in a Rat Model of Mild Traumatic Brain Injury
Jiyoun Lee
1BCDEF, Soeun Jeon 2ABCDE, Nara Kim 3BE, Sangmin Choi 3BE, Wangseok Do 3ABC, Jae-Rin Kim 4BCE, Eunsoo Kim 34AC, Jeong-Min Hong 34AC, Jiseok Baik 34ACDEFG*
DOI: 10.12659/MSM.942574
Med Sci Monit 2024; 30:e942574
Figure 2 Changes in the 50% mechanical withdrawal threshold with timeData are presented as the median with the 1st and 3rd quartiles. The Conover test was performed for post hoc multiple comparisons. Group S, sham surgery; Group T, traumatic brain injury; Group K, Intrathecal ketamine group; POD, postoperative day. * P<0.05 compared with Group S. # P<0.05 compared with Group T. The graphs in this figure were produced using MedCalc version18.11.6 (MedCalc Software bvba, Ostend, Belgium).