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01 February 2024: Animal Study

Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mechanical Allodynia in a Rat Model of Mild Traumatic Brain Injury

Jiyoun Lee 1BCDEF* , Soeun Jeon 2ABCDE* , Nara Kim 3BE , Sangmin Choi 3BE , Wangseok Do 3ABC , Jae-Rin Kim 4BCE , Eunsoo Kim 34AC , Jeong-Min Hong 34AC , Jiseok Baik 34ACDEFG*

DOI: 10.12659/MSM.942574

Med Sci Monit 2024; 30:e942574

Figure 2 Changes in the 50% mechanical withdrawal threshold with timeData are presented as the median with the 1st and 3rd quartiles. The Conover test was performed for post hoc multiple comparisons. Group S, sham surgery; Group T, traumatic brain injury; Group K, Intrathecal ketamine group; POD, postoperative day. * P<0.05 compared with Group S. # P<0.05 compared with Group T. The graphs in this figure were produced using MedCalc version18.11.6 (MedCalc Software bvba, Ostend, Belgium).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750