Potential of Gut Microbial Metabolites in Treating Osteoporosis and Obesity: A Network Pharmacology and Bioinformatics Approach

Md. Niaj Morshed; Md. Rezaul Karim; Reshmi Akter; Safia Iqbal; Ramya Mathiyalagan; Jong Chan Ahn; Deok Chun Yang; Joong Hyun Song; Se Chan Kang; Dong Uk Yang

doi:10.12659/MSM.942899

10 March 2024 : Database Analysis

Potential of Gut Microbial Metabolites in Treating Osteoporosis and Obesity: A Network Pharmacology and Bioinformatics Approach

Md. Niaj Morshed

^1ACEF, Md. Rezaul Karim^12BE, Reshmi Akter^1CDE, Safia Iqbal^1DF, Ramya Mathiyalagan^1CDF, Jong Chan Ahn^1BD, Deok Chun Yang^13CF, Joong Hyun Song^4CD, Se Chan Kang^1DFG*, Dong Uk Yang^15BFG

DOI: 10.12659/MSM.942899

Med Sci Monit 2024; 30:e942899

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Figure 7 3D Interactions of Obesity-related targets-their related metabolites and control (Rosiglitazone). (A) HMOX1-10-Oxo-11-octadecenoic acid (10308378), (B) HMOX1-Rosiglitazone (77999), (C) IL18-Equol (91469), (D) IL18-Indole (798), (E) IL18-Rosiglitazone (77999), (F) TP53-Compound K (9852086), (G) TP53-Urolithin A (5488186), (H) TP53-Rosiglitazone (77999), (I) MAPK8-genipin (442424), and (J) MAPK8-Rosiglitazone (77999), (K) G6PD-Urolithin A (5488186), (L) G6PD-Rosiglitazone (77999). All the figures were generated using BIOVIA Discovery Studio Visualizer v19.1 (BIOVIA).

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Potential of Gut Microbial Metabolites in Treating Osteoporosis and Obesity: A Network Pharmacology and Bioinformatics Approach

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