Differential Inflammatory Responses in Adult and Pediatric COVID-19 Patients: Implications for Long-Term Consequences and Anti-Inflammatory Treatment

Kacper Toczyłowski; Dawid Lewandowski; Diana Martonik; Anna Moniuszko-Malinowska; Ewelina Kruszewska; Anna Parfieniuk-Kowerda; Robert Flisiak; Artur Sulik

doi:10.12659/MSM.944052

31 May 2024 : Clinical Research

Differential Inflammatory Responses in Adult and Pediatric COVID-19 Patients: Implications for Long-Term Consequences and Anti-Inflammatory Treatment

Kacper Toczyłowski

^1ACDEFG*, Dawid Lewandowski^1AB, Diana Martonik

^2BE, Anna Moniuszko-Malinowska

^3ABE, Ewelina Kruszewska

^3BE, Anna Parfieniuk-Kowerda

^2BE, Robert Flisiak

^2BE, Artur Sulik

^1ABDE

DOI: 10.12659/MSM.944052

Med Sci Monit 2024; 30:e944052

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Figure 2 Before-after plots of serum matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), extracellular matrix metalloproteinase inducer (EMMPRIN), and tumor necrosis factor-alpha (TNF-α) concentrations in adult COVID-19 patients. Within each subplot, lines connect paired data points from the same patient, comparing protein concentrations at 2 time points: T1 (upon admission) and T2 (after symptom resolution and before discharge). Statistical significance assessed using the Wilcoxon matched-pairs signed-rank test is denoted by brackets above the graphs, with corresponding P values.

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Differential Inflammatory Responses in Adult and Pediatric COVID-19 Patients: Implications for Long-Term Consequences and Anti-Inflammatory Treatment

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