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09 July 2025 : Review article  

Advances in Neuromodulation Techniques for Aphasia Rehabilitation: A Comprehensive Review

Jiayi Xia ADEFG 1, Yeping Chen BCFG 1, Song Pei ADEF 2*, Chunlei Shan ADEF 3,4,5, Jingjing Zhang EF 3, Zhiqing Zhou EF 3, Jiali Wu EF 3, Yao Lu BC 1, Yiyi Chen BC 1, Yunjia Chen DF 1

DOI: 10.12659/MSM.947213

Med Sci Monit 2025; 31:e947213

Figure 1 Schematic illustration of neuromodulation techniques applied in aphasia rehabilitation (WPS Office, 12.2.0, Kingsoft Office Software Corporation Limited). This figure illustrates the application of 3 neuromodulation techniques in aphasia rehabilitation: (A) Transcranial direct current stimulation (tDCS) – delivering low-intensity electrical current via scalp electrodes to modulate cortical excitability, typically enhancing left hemisphere language areas or inhibiting right hemisphere homologs; (B) Transcranial magnetic stimulation (TMS) – applying repetitive magnetic pulses to stimulate or inhibit targeted cortical regions (eg, Broca’s area), using low-frequency (inhibitory) or high-frequency (excitatory) protocols; (C) Mirror neuron system (MNS) therapy – engaging language-related sensorimotor circuits through action observation and imitation tasks, aiming to enhance speech and communication functions behaviorally. tDCS – transcranial direct current stimulation; TMS – transcranial magnetic stimulation; MNS – mirror neuron system.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750