A Cross-Sectional Observational Study to Compare the Role of Ultrasound with Mammography in Women Identified at High Risk for Breast Cancer in a Population in China

04 May 2020: Clinical Research

Peili An ^BCF , Shujuan Zhong ^BCF , Rong Zhang ^ACF , Xiaoxia Hou ^ABC , Ruru Xi ^ADF , Yingjin Wang ^CEF*

DOI: 10.12659/MSM.919777

Med Sci Monit 2020; 26:e919777

Table 2 Specification for diagnostic parameters of adopted modalities.

BI-RADS scale	Diagnostic method							Comparisons between mammography and ultrasound	Comparisons between mammography and ultrasound + mammography
BI-RADS scale	Biopsies/histopathology	Ultrasound		Mammography		Ultrasound + mammography		Comparisons between mammography and ultrasound
Numbers of women enrolled	155	1,687	*p-value	1,687	*p-value	1,687	*p-value	p-value	p-value
0	0 (0)	1,037 (61)	N/A	1,094 (65)^**	N/A	945 (56)^**	N/A	0.046
1	N/A	201 (12)	N/A	189 (11)	N/A	220 (13)	N/A	0.554	0.114
2	N/A	142 (8)	N/A	115 (7)	N/A	202 (12)^**	N/A	0.092
3	N/A	153 (9)	N/A	148 (9)	N/A	165 (10)	N/A	0.809	0.342
4	92 (59)	91 (6)	0.962	79 (5)	0.645	92 (5)	N/A	0.3866	0.346
5	63 (41)	63 (4)	0.962	62 (3)	0.645	63 (4)	N/A	0.927	0.927
N/A – not applicable. Variables are shown as frequency (percentage). ^* Comparison with respect to biopsies/histopathology. BI-RADS – The Breast Imaging-Reporting and Data System. 0 – Inconclusive results; 1 – tumor was absent; 2 – benign tumor; 3 – probably benign; 4 – suspicious abnormality; 5 – highly suggestive of malignant. Fischer’s exact test or Chi-square independence test was used for statistical analysis. ^** Significant difference with respect to mammography.