26 July 2020: Meta-Analysis
Integrated Analysis of Three Publicly Available Gene Expression Profiles Identified Genes and Pathways Associated with Clear Cell Renal Cell Carcinoma
YuPing Han 1ACD , LinLin Wang 2EF , Ye Wang 3AB*DOI: 10.12659/MSM.919965
Med Sci Monit 2020; 26:e919965
Table 1 Top 10 hub genes based on netweenness centrlity, closeness centrality and degree.
| Gene | Betweenness centrality | Closeness centrality | Degree | LogFC |
|---|---|---|---|---|
| CDK1 | 0.148 | 0.283 | 23 | 1.391 |
| QSOX1 | 0.083 | 0.294 | 22 | 0.978 |
| CCNA2 | 0.056 | 0.266 | 21 | 1.083 |
| AURKB | 0.018 | 0.248 | 18 | 0.674 |
| CCNB1 | 0.024 | 0.252 | 18 | 0.719 |
| MAD2L1 | 0.006 | 0.244 | 16 | 0.904 |
| TF | 0.045 | 0.271 | 16 | 1.004 |
| BUB1B | 0.009 | 0.244 | 16 | 1.203 |
| C3AR1 | 0.048 | 0.273 | 16 | 1.560 |
| FGG | 0.053 | 0.282 | 15 |