17 July 2020 : Laboratory Research
Expression of the C677T Polymorphism of the 5, 10-Methylenetetrahydrofolate Reductase (MTHFR) Gene in Patients with Carotid Artery Atherosclerosis
Anying Li1BG, Wei Huang1C, Qiong Yang1AE, Liping Peng1BD, Qiang Liu2ADE*DOI: 10.12659/MSM.920320
Med Sci Monit 2020; 26:e920320
Table 4 Comparison of MTHFR C667 allele frequency and genotype frequency.
| Genotype | χ2 | P | Alleles | χ2 | P | ||||
|---|---|---|---|---|---|---|---|---|---|
| CC (%) | CT (%) | TT (%) | C (%) | T (%) | |||||
| Stable plaque | 12 (14.46) | 44 (53.01) | 27 (32.53) | 68 (40.96) | 98 (59.04) | 3.943 | 0.047 | ||
| Unstable plaque | 28 (22.05) | 24 (18.90) | 75 (59.05) | 80 (31.50) | 174 (68.50) | ||||
| Folate level (ng/L) | 7.45±2.34 | 7.25±1.21 | 6.94±1.31 | 6.81±1.28 | 6.79±1.31 | 4.129 | 0.129 | ||
| B12 (pg/L) | 235.25±137.21 | 203.51±136.25 | 211.25±129.55 | 165.85±128.58 | 166.95±130.55 | 2.142 | 0.081 | ||
| Hcy (μmol/L) | 24.24±2.04 | 23.24±2.15 | 23.35±2.21 | 22.24±2.04* | 20.85±1.92 | 3.212 | 0.522 | ||