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15 June 2020: Clinical Research

LncRNA LINC00152 Increases the Aggressiveness of Human Retinoblastoma and Enhances Carboplatin and Adriamycin Resistance by Regulating MiR-613/Yes-Associated Protein 1 (YAP1) Axis

Ying Wang CDE* , Danli Xin ABCE , Lei Zhou BCDF

DOI: 10.12659/MSM.920886

Med Sci Monit 2020; 26:e920886

Table 1 Association of LINC00152 expression with clinicopathologic characteristics of retinoblastoma patients.

ParameterCaseLINC00152 expressionP value*
High (n=18)Low (n=18)
Age (years)
Tumor size (mm)
Degree of differentiation
 Well and moderately13760.760
ICRB staging system
 Group A–C144100.008
 Group D–E22148
Choroidal invasion
Optic nerve invasion
* Chi-square test.
ICRB – International Classification of Retinoblastoma.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750