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15 June 2020: Clinical Research

LncRNA LINC00152 Increases the Aggressiveness of Human Retinoblastoma and Enhances Carboplatin and Adriamycin Resistance by Regulating MiR-613/Yes-Associated Protein 1 (YAP1) Axis

Ying Wang CDE* , Danli Xin ABCE , Lei Zhou BCDF

DOI: 10.12659/MSM.920886

Med Sci Monit 2020; 26:e920886

Table 1 Association of LINC00152 expression with clinicopathologic characteristics of retinoblastoma patients.

ParameterCaseLINC00152 expressionP value*
High (n=18)Low (n=18)
Sex
 Female16790.714
 Male20119
Age (years)
 ≤2199100.682
 >22798
Tumor size (mm)
 ≤15176110.016
 >1519127
Degree of differentiation
 Well and moderately13760.760
 Poorly231112
ICRB staging system
 Group A–C144100.008
 Group D–E22148
Choroidal invasion
 No18612
 Yes18126
Optic nerve invasion
 No166100.003
 Yes20128
* Chi-square test.
ICRB – International Classification of Retinoblastoma.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750