24 June 2020: Clinical Research
Comprehensive Analysis of Candidate Diagnostic and Prognostic Biomarkers Associated with Lung Adenocarcinoma
Jingyuan Li 1AE , Xingyuan Liu 23CF , Zan Cui 1B , Guanying Han 1DG*DOI: 10.12659/MSM.922070
Med Sci Monit 2020; 26:e922070
Table 6 KEGG pathway analysis of uDEGs and dDEGs.
| ID | KEGG_PATHWAY description | Count | % | P-value |
|---|---|---|---|---|
| uDEGs | ||||
| hsa04115 | p53 signaling pathway | 8 | 5.48 | 1.6E-06 |
| hsa04110 | Cell cycle | 8 | 5.48 | 9.1E-05 |
| hsa04114 | Oocyte meiosis | 5 | 3.42 | 1.6E-02 |
| hsa04914 | Progesterone-mediated oocyte maturation | 4 | 2.74 | 4.0E-02 |
| hsa05219 | Bladder cancer | 3 | 2.05 | 4.9E-02 |
| dDEGs | ||||
| hsa05200 | Pathways in cancer | 23 | 5.35 | 6.4E-04 |
| hsa04024 | cAMP signaling pathway | 15 | 3.49 | 7.2E-04 |
| hsa04080 | Neuroactive ligand-receptor interaction | 15 | 3.49 | 1.5E-02 |
| hsa04550 | Signaling pathways regulating pluripotency of stem cells | 12 | 2.79 | 1.1E-03 |
| hsa04514 | Cell adhesion molecules (CAMs) | 12 | 2.79 | 1.3E-03 |
| KEGG – Kyoto Encyclopedia of Genes and Genomes; uDEGs – upregulated differentially expressed genes; dDEGs – downregulated differentially expressed genes. | ||||