02 July 2020 : Clinical Research
Tumor Location and Survival Outcomes in Lung Adenosquamous Carcinoma: A Propensity Score Matched Analysis
Xinlin Shi1ABCEF, Xiangrong Shao1B, Yawen Zhang1BC, Feng Wu1AE*, Yujian Tao1ABDOI: 10.12659/MSM.922138
Med Sci Monit 2020; 26:e922138
Table 2 Univariate and multivariate analyses of OS after PSM.
| Variables | Univariate analysis | Multivariate analysis |
|---|---|---|
| P-value | HR (95% CI), P-value | |
| Age | 0.339 | Not included |
| <60 | ||
| ≥60 | ||
| Sex | 0.328 | Not included |
| Male | ||
| Female | ||
| Race | 0.662 | Not included |
| Black | ||
| White | ||
| Other | ||
| Primary site | 0.038 | 0.041 |
| Main bronchus | Reference | |
| Peripheral | 1.362 (1.012–1.834) | |
| Grade | 0.917 | Not included |
| I–II | ||
| III–IV | ||
| Unknown | ||
| AJCC stage | <0.001 | 0.007 |
| I | Reference | |
| II | 2.873 (1.045–7.899) 0.041 | |
| III | 3.129(1.204–8.126) 0.019 | |
| IV | 4.160 (1.582–10.938) 0.004 | |
| T stage | <0.001 | 0.004 |
| T1 | Reference | |
| T2 | 1.510 (0.778–2.928) 0.223 | |
| T3 | 0.950 (0.403–2.239) 0.906 | |
| T4 | 2.203 (1.155–4.205) 0.017 | |
| N stage | 0.182 | Not included |
| N0 | ||
| N1 | ||
| N2 | ||
| N3 | ||
| M stage | <0.001 | Not included |
| M0 | ||
| M1 | ||
| Surgery | <0.001 | 0.002 |
| No/Unknown | Reference | |
| Yes | 0.419 (0.243–0.722) | |
| Radiation | 0.535 | Not included |
| No/Unknown | ||
| Yes | ||
| Chemotherapy | <0.001 | <0.001 |
| No/Unknown | Reference | |
| Yes | 0.336 (0.244–0.464) | |
| OS – overall survival; PSM – Propensity Score Matching; HR – hazard ratio; CI – confidence interval; AJCC – American Joint Committee on Cancer. | ||