Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

07 September 2020: Clinical Research

Effect of Comorbidity on Outcomes of Patients with Advanced Non-Small Cell Lung Cancer Undergoing Anti-PD1 Immunotherapy

Xianghua Zeng 123CDEG* , Shicong Zhu 12BCD* , Cheng Xu 4CF , Zhongyu Wang 12CD , Xingxing Su 12CD , Dong Zeng 12CD , Haixia Long 12AF* , Bo Zhu 12AG*

DOI: 10.12659/MSM.922576

Med Sci Monit 2020; 26:e922576

Table 1 The Charlson comorbidity index weights.

WeightComorbidity conditions
1 pointHistory of myocardial infarction; Congestive heart failure; Peripheral disease (includes aortic aneurysm ≥6 cm); Cerebrovascular disease (with mild or no residua or transient ischemic attack); Dementia; Chronic pulmonary disease; Connective tissue disease; Peptic ulcer disease; Mild liver diseases (no portal hypertension, including chronic hepatitis); Diabetes without end-organ damage
2 pointsHemiplegia; Moderate or severe renal disease; Diabetes with end-organ damage; Other tumors without metastasis (exclude if >5 years from diagnosis of non-small cell lung cancer); Leukemia (acute or chronic); Lymphoma
3 pointsModerate or severe liver disease
6 pointsOther metastatic solid tumors (exclude if >5 years from diagnosis of non-small cell lung cancer); Acquired immunodeficiency syndrome (not just human immunodeficiency virus positive)
33 pointsMaximum comorbidity score

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750