27 July 2020: Clinical Research
Clinical Characteristics and Prognosis of Osteoclast-like Giant Cell Tumors of the Pancreas Compared with Pancreatic Adenocarcinomas: A Population-Based Study
Mingfang Xu 1ABCDE , Wei Chen 2ABCD , Dong Wang 1ABCD , Mao Nie 3EFG*DOI: 10.12659/MSM.922585
Med Sci Monit 2020; 26:e922585
Table 1 Demographic and clinic characteristics of patients with OGTP and PA between 2001 and 2016 in SEER database demographic.
| Diagnosis | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
| OGTP (%) | PA (%) | P-value | OGTP (%) | PA (%) | P-value | |
| N | 47 | 73150 | 47 | 141 | ||
| Age at diagnosis | 0.001 | 0.32 | ||||
| 2 (4.2) | 4467 (6.1) | 2 (4.2) | 21 (14.9) | |||
| 50–59 | 17 (36.2) | 13186 (18.0) | 17 (36.2) | 47 (33.3) | ||
| 60–69 | 19 (40.4) | 21311 (29.1) | 19 (40.4) | 49 (34.8) | ||
| 70–79 | 5 (10.6) | 21554 (29.5) | 5 (10.6) | 12 (8.5) | ||
| ≥80 | 4 (8.5) | 12632 (17.3) | 4 (8.5) | 12 (8.5) | ||
| Race | 0.638 | 0.86 | ||||
| White | 37 (78.7) | 59010 (80.7) | 37 (78.7) | 116 (82.3) | ||
| Black | 5 (10.6) | 8895 (12.2) | 5 (10.6) | 13 (9.2) | ||
| Other | 5 (10.6) | 5245 (7.2) | 5 (10.6) | 12 (8.5) | ||
| Sex | 0.003 | 0.63 | ||||
| Female | 33 (70.2) | 35616 (48.7) | 33 (70.2) | 106 (75.2) | ||
| Male | 14 (29.8) | 37524 (51.3) | 14 (29.8) | 35 (24.8) | ||
| Year of diagnosis | 0.022 | 0.46 | ||||
| 2001–2005 | 5 (10.6) | 19054 (26.0) | 5 (10.6) | 11 (7.8) | ||
| 2006–2010 | 15 (31.9) | 24422 (33.4) | 15 (31.9) | 59 (41.8) | ||
| 2011–2016 | 27 (57.4) | 29674 (40.6) | 27 (57.4) | 71 (50.4) | ||
| Site | 0.821 | 0.74 | ||||
| Head | 24 (51.1) | 38551 (52.7) | 24 (51.1) | 78 (55.3) | ||
| Other | 23 (48.9) | 34593 (47.3) | 23 (48.9) | 63 (44.7) | ||
| Grade | 0.70 | |||||
| I–II | 0 (0) | 13493 (18.4) | 0 (0) | 2 (1.4) | ||
| III–IV | 41 (87.2) | 11045 (15.1) | 41 (87.2) | 123 (87.2) | ||
| Unkown | 6 (12.8) | 48612 (66.5) | 6 (12.8) | 16 (11.3) | ||
| Stage | 0.95 | |||||
| Localize | 9 (19.1) | 5958 (8.1) | 9 (19.1) | 30 (21.3) | ||
| Regional | 27 (57.4) | 25103 (34.3) | 27 (57.4) | 78 (55.3) | ||
| Distant | 11 (23.4) | 42089 (57.5) | 11 (23.4) | 33 (23.4) | ||
| Status | ||||||
| Alive | 11 (23.4) | 3856 (5.3) | 11 (23.4) | 28 (19.9) | 0.76 | |
| Dead | 36 (76.6) | 69294 (94.7) | 36 (76.6) | 113 (80.1) | ||
| N staging | 0.58 | |||||
| N0 | 30 (63.8) | 31732 (43.4) | 30 (63.8) | 87 (61.7) | ||
| N1 | 8 (17.0) | 21055 (28.8) | 8 (17.0) | 33 (23.4) | ||
| Unknown | 9 (19.1) | 20363 (27.8) | 9 (19.1) | 21 (14.9) | ||
| M staging | 0.83 | |||||
| M0 | 32 (68.1) | 27974 (38.2) | 32 (68.1) | 96 (68.1) | ||
| M1 | 8 (17.0) | 32956 (45.1) | 8 (17.0) | 28 (19.9) | ||
| Unknown | 7 (14.9) | 12220 (16.7) | 7 (14.9) | 17 (12.1)) | ||
| Surgery | 0.72 | |||||
| yes | 33 (70.2) | 11281 (15.4) | 33 (70.2) | 93 (66) | ||
| No | 14 (29.8) | 61869 (84.6) | 14 (29.8) | 93 (66) | ||
| OGTP – osteoclast-like giant cell tumor of the pancreas; PA – pancreatic adenocarcinoma; PSM – propensity score matching; SEER – Surveillance, Epidemiology and End Results. | ||||||