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04 July 2020: Clinical Research

Implementation of Thromboelastometry for Coagulation Management in Isolated Traumatic Brain Injury Patients Undergoing Craniotomy

Marius Rimaitis 1ABCDEFG* , Diana Bilskienė 1ABE , Tomas Tamošuitis 2BE , Rimantas Vilcinis 2BDE , Kęstutis Rimaitis 1DE , Andrius Macas 1ADEG

DOI: 10.12659/MSM.922879

Med Sci Monit 2020; 26:e922879

Table 6 Outcome parameters of the control and case group patients.

ControlsCasesP
1 Normal (n=39)2 CP (n=26)3 All (N=65)4 Normal (n=35)5 CP (n=34)6 All (N=69)1 vs. 42 vs. 53 vs. 6
Progressive injuryHemorrhagic18 (46.2)13 (50)31 (47.7)* 10 (28.6)11 (32.4)21 (30.4)* 0.1190.167*
Ischemic6 (15.4)14 (53.8)20 (30.8)5 (14.3)13 (38.2)18 (26.1)0.8940.2280.548
Edematous2 (5.1)3 (11.5)5 (7.7)4 (11.4)6 (17.6)10 (14.5)0.3220.5110.212
Re-intervention6 (15.8)10 (40)* 16 (25.4)5 (14.3)4 (12.9)* 9 (13.6)0.858* 0.091
Length of hospital stay (survivors)17 (10–27)25 (14–32)22 (10.75–27.25)17 (9.75–25.75)19 (11–24.5)17 (11–24)0.6830.1010.277
GCSDay 312 (7–15)9 (5–14)11 (5–14)13 (6–15)11.5 (5–15)12.5 (5–15)0.4830.2920.289
Day 713 (8.5–15)10.5 (5–14.75)12 (5–15)15 (6–15)13 (5.5–15)13 (6–15)0.2940.2710.205
At discharge15 (12–15)14 (8–15)15 (10.75–15)15 (13.5–15)15 (13–15)15 (13–15)0.3860.1900.158
Clinical outcomeFavorable (GOS 4–5)19 (48.7)4 (15.4)23 (35.4)19 (54.3)13 (38.2)32 (46.4)0.6320.0520.196
Poor (GOS 1–3)20 (51.3)22 (84.6)42 (64.6)16 (45.7)21 (61.8)37 (53.6)
Death4 (10.3)11 (42.3)15 (23.1)5 (14.3)13 (38.2)18 (26.1)0.5960.7500.686
Continuous variables are reported as median (interquartile range); categorical variables are reported in terms of frequency (percentage). Superscript numbers (1 to 6) mark columns to clarify comparisons.
* Statistically significant differences.
CP – coagulopathy; GCS – Glasgow coma score; GOS – Glasgow outcome score.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750