07 August 2020>: Animal Study
The Release of Norepinephrine in C57BL/6J Mice Treated with 6-Hydroxydopamine (6-OHDA) is Associated with Translocations in Enteric via the QseC Histidine Kinase Receptor
Jun Meng 1ACDEF , Huamei Chen 2BCF , Qin Lv 2BC , Xiaodan Luo 2BC , Kun Yang 2AG*DOI: 10.12659/MSM.922986
Med Sci Monit 2020; 26:e922986
Table 2 Bacterial translocation after administration of 6-hydroxydopamine.
Bacterial translocation rate | CFU/g (median, range) | |||
---|---|---|---|---|
MLN | Spleen | Liver | ||
Blank-S | 0/6 | 0 (0) | 0 (0) | 0 (0) |
B-S | 1/6 | 0 (0~98) | 0 (0) | 0 (0~77) |
Δ-S | 1/6 | 0 (0~62) | 0 (0) | 0 (0) |
C-S | 1/6 | 0 (0~72) | 0 (0) | 0 (0~55) |
B-6OH | 5/6** | 240 (0~590)** | 113 (0~270)** | 120 (0~290)** |
Δ-6OH | 3/6* | 38 (0~300)* | 0 (0~150)* | 0 (0~208)* |
C-6OH | 4/6 | 135 (0~500)*** | 85 (0~250)*** | 64 (0~300)*** |
Blank-S – blank+sham group; B-S – BW25113+sham group; Δ-S – Δ+sham group; C-S – Δ pQseC+sham group; B-6OH – BW25113+6-OHDA group; Δ-6OH – Δ+6-OHDA group; C-6OH – Δ pQseC+6-OHDA group. MLN – mesenteric lymph nodes. * ** *** |