Prognostic Determinants Analysis and Nomogram for Bone Malignant Vascular Tumors: A Surveillance, Epidemiology and End Results (SEER) Analysis

10 July 2020 : Database Analysis

Sunli Hu^12ABCDEFG, Xiangyang Wang^1AB*

DOI: 10.12659/MSM.923305

Med Sci Monit 2020; 26:e923305

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Table 2 Multivariate analysis of prognostic factors in patients with primary malignant vascular tumors of bone.

Factor	Category	Multivariate

		N	HR (95% CI)	p-Value
Age (years)	χ=18.997, P=0.000
	<64	120	Reference

	≥64	146	3.636 (1.955–6.762)	0.000^*

Sex	χ=4.033, P=0.0225
	Female	106	Reference

	Male	160	1.802 (1.032–3.004)	0.046^*

Primary site	χ=20.231, P=0.0035
	Trunk	13	Reference

	Limbs	140	1.108 (0.595–2.603)	0.747

	Other	15	0.813 (0.508–0.932)	0.016^*

	Skull	26	2.600 (1.584–4.268)	0.000^*

	Spine	71	0.680 (0.398–1.163)	0.159

Metastasis	χ=25.554, P=0.000
	No	132	Reference

	Yes	105	3.076 (1.983–4.771)	0.000^*

	Unknown	29	1.557 (1.003–2.417)	0.051

Histologic type	χ=69.2, P=0.0000
	Angiosarcoma	152	Reference

	Hemangioendothelioma	46	0.250 (0.129–0.485)	0.000^*

	Epithelioid hemangioendotheliomas	49	0.453 (0.283–0.727)	0.001^*

	Hemangiopericytoma	19	0.498 (0.265–0.937)	0.031^*

Surgery	χ=20.195, P=0.0008
	Yes	153	Reference

	No	113	1.473 (1.239–1.751)	0.000^*

Grade	χ=51.293, P=0.0016
	Low	56	Reference

	High	69	3.029 (2.101–4.366)	0.003^*

	Unknown	141	2.091 (1.364–3.204)	0.027^*
^* Indicates statistical significance (p

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