Dioscin Attenuates Interleukin 1β (IL-1β)-Induced Catabolism and Apoptosis via Modulating the Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling in Human Nucleus Pulposus Cells

25 August 2020 : Clinical Research

Longhui Wang^1DEF, Yuntao Gu^1BE, Hai Zhao^1CEF, Rong Chen^1BD, Wensheng Chen^1BF, Hao Qi^1BE, Weisong Gao^1ABG*

DOI: 10.12659/MSM.923386

Med Sci Monit 2020; 26:e923386

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Table 1 Primers of targeted genes.

	Forward	Reverse
MMP3	CTGGCCTGCTGGCTCATGCTT	GCAGGGTCCTTGGAGTGGTCA
MMP13	AGCCACTTTATGCTTCCTGATG	GATGTTTAGGGTTGGGGTCTTC
ADAMTS4	CCTGGCAAGGACTATGATGCTGA	GGGCGAGTGTTTGGTCTGG
ADAMTS5	CGCTCTCTGGCTGTCTTTGAC	AGCAGTGGCTTTAGGGTGTAGC
Collagen II	CTCAAGTCGCTGAACAACCA	GTCTCCGCTCTTCCACTCTG
Aggrecan	GTCAGATACCCCATCCACACTC	CATAAAAGACCTCACCCTCCAT
IL-6	ATGAACTCCTTCTCCACAAGC	CTACATTTGCCGAAGAGCCCTCAGGCTGGACTG
TNF-α	AGGCGGTGCTTGTTCCTCA	GTTCGAGAAGATGATCTGACTGCC
β-actin	ATTGCCGACAGGATGCAGAA	GCTGATCCACATCTGCTGGA

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