Identification of Hub Genes Associated with Hypertension and Their Interaction with miRNA Based on Weighted Gene Coexpression Network Analysis (WGCNA) Analysis

05 September 2020: Database Analysis

Zongjin Li ^1ABCDEF , Jacqueline Chyr ^2EF , Zeyu Jia ^3BF , Lina Wang ^4EF , Xi Hu ^4DF , Xiaoming Wu ^4AC* , Changxin Song ^5DG*

DOI: 10.12659/MSM.923514

Med Sci Monit 2020; 26:e923514

Table 1 Hub genes (MiRNAs) in key modules.

Modules	Name	DEGs	GS	MM	Log2FC
M	RPS28	Down	−0.65	0.884	−0.282
M	RPL21	Down	−0.555	0.863	−0.290
M	LOC442727(PTMAP10)	Down	−0.527	0.895	−0.345
M	LOC100129599(RPS29P14)	Down	−0.441	0.848	−0.303
M	TBXAS1	Down	−0.517	0.926	−0.316
M	FCER1G	Down	−0.597	0.922	−0.478
M	CFP	Down	−0.550	0.867	−0.347
M	FURIN	Down	−0.544	0.872	−0.316
M	PECAM1	Down	−0.487	0.844	−0.243
M	IGSF6	Down	−0.485	0.860	−0.412
M	NCF1C	Down	−0.450	0.879	−0.354
M	LOC285296(UNC93B3)	Down	−0.451	0.852	−0.174
M	hsa-miR-1268a/hsa-miR-1268b	Up	0.416	0.987	0.550
M	hsa-miR-513c-3p	Up	0.354	0.984	0.641
M	hsa-miR-4799-5p	Up	0.392	0.975	1.054
M	hsa-miR-296-3p	Up	0.417	0.974	0.408
M	hsa-miR-5195-5p	Up	0.429	0.972	0.915
M	hsa-miR-219-2-3p	Up	0.451	0.972	0.746
M	hsa-miR-548d-5p	Up	0.399	0.968	0.901