05 September 2020 : Database Analysis
Identification of Hub Genes Associated with Hypertension and Their Interaction with miRNA Based on Weighted Gene Coexpression Network Analysis (WGCNA) Analysis
Zongjin Li1ABCDEF, Jacqueline Chyr2EF, Zeyu Jia3BF, Lina Wang4EF, Xi Hu4DF, Xiaoming Wu4AC, Changxin Song5DG*DOI: 10.12659/MSM.923514
Med Sci Monit 2020; 26:e923514
Table 2 Top 10 in network MiRNA-gene ranked by MCC method.
| Rank | Name | Score | DEGs |
|---|---|---|---|
| 1 | hsa-miR-548am-3p | 14 | Up |
| 2 | hsa-miR-513c-3p | 11 | Up |
| 2 | hsa-miR-182-5p | 11 | Up |
| 4 | hsa-miR-548d-5p | 8 | Up |
| 4 | IGF1R | 8 | Down |
| 6 | GSK3B | 7 | Up |
| 7 | FOXO1 | 6 | Up |
| 7 | PRKAR2B | 6 | Up |
| 7 | HIF1A | 6 | Down |
| 7 | PIK3R1 | 6 | Up |
| miRNA – microRNA; MCC – Maximal Clique Centrality function. | |||