Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis

Dongdong Yuan; Xiangfen Shi; Liping Guo; Gaobiao Wang; Yujie Zhao; Yuling Yang; Hanjuan Zhang; Qiong Huang; Yiqiang Yuan

doi:10.12659/MSM.923758

16 June 2020 : Clinical Research

Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis

Dongdong Yuan^1ABCD, Xiangfen Shi^2BCD, Liping Guo^1BF, Gaobiao Wang^1BF, Yujie Zhao^1B, Yuling Yang^1B, Hanjuan Zhang^1B, Qiong Huang^1B, Yiqiang Yuan^1AE*

DOI: 10.12659/MSM.923758

Med Sci Monit 2020; 26:e923758

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Table 4 Distribution of arachidonic acid-induced platelet aggregation rates in patients without reported bleeding events.

ACA-induced platelet aggregation (%)	Patients (n=25)	%
50–30	7	30
50–25	11	45
50–20	15	60
50–18	20	80
50–5	25	100
ACA – arachidonic acid.

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Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis

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