09 September 2020 : Clinical Research
Clinical Characteristics and Treatment Outcomes in Human Immunodeficiency Virus (HIV)-Infected Patients with Liver Abscess: A Retrospective Study of 53 Patients
Wei Zhang1AE, Hongwei Yu1BC, Na Luo2BC, Zhongjie Hu1AE*DOI: 10.12659/MSM.923761
Med Sci Monit 2020; 26:e923761
Table 3 Laboratory results of 53 HIV-infected patients with liver abscess.
| Variable | Total (n=53) | Improvement group (n=48) | Non-improvement group (n=5) | t or χ2 | p |
|---|---|---|---|---|---|
| WBC count >9.5×10/L | 26/53 (49.06%) | 24/48 (50.00%) | 2/5 (40.00%) | 0 | 1 |
| Neutrophil% >75.0% | 28/53 (52.83%) | 25/48 (52.08%) | 3/5 (60.00%) | 0 | 1 |
| Hb <130 g/L | 46/53 (86.79%) | 41/48 (85.42%) | 5/5 (100.00%) | 0.05 | 0.824 |
| PLT >350×10/L) | 17/53 (32.08%) | 17/48 (35.42%) | 0/5 (0) | 1.235 | 0.266 |
| PLT <125×10/L) | 3/53 (5.66%) | 2/48 (4.17%) | 1/5 (20.00%) | 0.195 | 0.659 |
| ALT >50 U/L | 17/52 (32.69%) | 14/47 (29.79%) | 3/5 (60.00%) | 0.753 | 0.386 |
| AST >40 U/L | 28/52 (53.85%) | 24/47 (51.06%) | 4/5 (80.00%) | 0.581 | 0.446 |
| TBIL >21.8 umol/L | 12/52 (23.08%) | 12/47 (25.53%) | 0/5 (0) | 0.533 | 0.465 |
| DBIL >7.1 umol/L | 17/52 (32.69%) | 15/47 (31.92%) | 2/5 (40.00%) | 0 | 1 |
| ALB <40 g/L | 45/51 (88.24%) | 41/47 (87.23%) | 4/4 (100.00%) | 0 | 1 |
| ALP >125 U/L | 24/45 (53.33%) | 22/42 (52.38%) | 2/3 (66.67%) | 0 | 1 |
| BUN >8 mmol/L | 2/52 (3.85%) | 1/47 (2.13%) | 1/5 (20.00%) | 0.566 | 0.452 |
| Crea >97 umol/L | 4/52 (7.69%) | 4/47 (8.51%) | 0/5 (0) | 0 | 1 |
| PT >12.8 s | 32/48 (66.67%) | 28/44 (63.64%) | 4/4 (100.00%) | 0.852 | 0.356 |
| PTA <80% | 31/48 (64.58%) | 28/44 (63.64%) | 3/4 (75.00%) | 0 | 1 |
| ESR >20 mm/H | 37/41 (90.24%) | 34/38 (89.47%) | 3/3 (100.00%) | 0 | 1 |
| CD4 T cells cells/ul | 328.09±236.19 | 335.40±236.44 | 258.00±248.14 | 0.694 | 0.491 |
| CD4 T cells distribution (%) | |||||
| CD4 T ≤200 cells/ul | 17 (32.08%) | 15 (31.25%) | 2 (40.00%) | 0 | 1 |
| CD4 T >200 cells/ul | 36 (67.92%) | 33 (68.75%) | 3 (60.00%) | ||
| Imaging findings(n, % or mean±SD) | |||||
| Single lesion | 40 (75.47%) | 37 (77.08%) | 3 (60.00%) | 0.089 | 0.756 |
| Multiple lesions | 13 (24.53%) | 11 (22.92%) | 2 (40.00%) | ||
| Gas formation | 7 (13.21%) | 7 (14.58%) | 0 (0) | 0.05 | 0.824 |
| Abscess location | |||||
| Left lobe | 9 (16.98%) | 6 (12.50%) | 3 (60.00%) | 4.27 | 0.039 |
| Right lobe | 33 (62.26%) | 33 (68.75%) | 0 (0) | 6.418 | 0.011 |
| Both lobes | 9 (16.98%) | 7 (14.58%) | 2 (40.00%) | 0.664 | 0.415 |
| Caudate lobe | 2 (3.77%) | 2 (4.17%) | 0 (0) | 0 | 1 |
| Maximal diameter of abscess | |||||
| ≤5 cm | 6 (11.32%) | 6 (12.50%) | 0 (0) | 1.798 | 0.407 |
| 5<≤10 cm | 31 (58.49%) | 27 (56.25%) | 4 (80.00%) | ||
| >10 cm | 16 (30.19%) | 15 (31.25%) | 1 (20.00%) | ||
| WBC – white blood cell count; Hb – hemoglobin; PLT – platelet; ALT – alanine aminotransferase; AST – aspartate aminotransferase; TBIL – total bilirubin; DBIL – direct bilirubin; ALB – albumin; ALP – alkaline phosphatase; BUN – blood urea nitrogen; Crea – serum creatinine; PT – prothrombin time; PTA – prothrombin activity; ESR – erythrocyte sedimentation rate. | |||||