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30 August 2020: Lab/In Vitro Research

Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism

Yidan Yan 1ABC , Jianmin Xu 2CDE , Guoxin Mao 3EFG*

DOI: 10.12659/MSM.923962

Med Sci Monit 2020; 26:e923962

Table 1 Relative primer sequences.

Gene namePrimer sequence
HER2aF: 5′-CCATCAAAGTGTTGAGGGAAAC-3′
R: 5′-AATCTGCATACACCAGTTCAGCA-3′
PI3KF: 5′-CATCACTTCCTCCTGCTCTAT-3′
R: 5′-CAGTTGTTGGCAATCTTCTTC-3′
AKTF: 5′-GGACAACCGCCATCCAGACT-3′
R: 5′-GCCAGGGACACCTCCATCTC-3′
P21F: 5′-CCATCGATGGCAGCTCTTGCAGAAGCTC-3′
R: 5′-GCTCTAGACTGGCCGGATTTGCGCGG-3′
MMP-9F: 5′-GAGACCGGTGAGCTGGATAG-3′
R: 5′-TACACGCGAGTGAAGGTGAG-3′
GAPDHF: 5′-GGTGAAGGTCGGAGTCAACG-3′
R: 5′-CAAAGTTGTCATGGATGACC-3′
HER2 – human epidermal growth factor receptor 2; PI3K – phosphatidylinositol 3-kinase; AKT – protein kinase B; MMP – matrix metalloproteinase; GAPDH – glyceraldehyde-3-phosphate dehydrogenase; F – forward; R – reverse.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750