17 June 2020: Clinical Research
Clinical and Demographic Characteristics of Cluster Cases and Sporadic Cases of Coronavirus Disease 2019 (COVID19) in 141 Patients in the Main District of Chongqing, China, Between January and February 2020
Peng Chen ABE* , Ying Zhang BCF* , Yongsheng Wen DE , Jinjun Guo BD , Weizhi Bai BCE , Jinwei Jia EF , Yu Ma ACG* , Yi Xu BDEG*DOI: 10.12659/MSM.923985
Med Sci Monit 2020; 26:e923985
Table 3 The clinical characteristics of cluster and sporadic cases of coronavirus disease 2019 (COVID-19) in the main district of Chongqing, China, from January 25th to February 25th, 2020.
| Characteristics | Cluster cases (N=90) | Sporadic cases (N=51) | P-value |
|---|---|---|---|
| Age (mean±SD) (years) | 50.1±8.2 | 42.0±7.7 | 0.01 |
| Gender, n (%) | |||
| Men | 43 (47.8) | 30 (58.8) | NS |
| Women | 47 (52.2) | 21 (41.2) | |
| Comorbidities | |||
| Hypertension | 25 (27.8) | 9 (17.6) | NS |
| Diabetes | 18 (20.0) | 8 (15.7) | NS |
| Coronary heart disease | 14 (15.6) | 9 (17.6) | NS |
| Chronic obstructive pulmonary disease | 10 (11.1) | 7 (13.7) | NS |
| Time from contact to illness | 8.3±3.2 | 7.1±3.8 | NS |
| Symptoms, n (%) | |||
| Fever | 36 (40) | 31 (60.8) | 0.02 |
| 37.3–38.0 | 25 (69.4) | 14 (45.2) | 0.04 |
| ≥38.0 | 11 (30.6) | 17 (54.8) | |
| Cough | 40 (44.4) | 29 (56.9) | NS |
| Fatigue | 9 (10) | 10 (19.6) | NS |
| Muscle ache | 9 (10) | 8 (15.7) | NS |
| Sore throat | 8 (8.9) | 6 (11.8) | NS |
| Headache | 8 (8.9) | 5 (9.8) | NS |
| Rhinorrhea | 7 (7.7) | 4 (7.8) | NS |
| Dyspnoea | 7 (7.8) | 7 (13.7) | NS |
| Nausea or vomiting | 6 (6.7) | 3 (6) | NS |
| Diarrhea | 3 (3.3) | 2 (3.9) | NS |
| Palpitations | 10 (11.1) | 6 (11.8) | NS |
| Asymptomatic | 29 (32.2) | 3 (5.9) | 0.00 |
| Clinical classification | |||
| Mild case | 41 | 16 | 0.02 |
| Moderate case | 44 | 25 | |
| Severe case | 5 | 10 | |
| Radiology examination | |||
| Bilateral lung involvement | 70 (77.8) | 41 (80.4) | NS |
| Typical chest CT manifestations | 66 (73.3) | 45 (88.2) | 0.04 |
| Laboratory examination | |||
| White blood cell count, ×10/L | |||
| ≤3.5 | 12 (13.3) | 5 (9.8) | NS |
| 3.5–9.5 | 71 (78.9) | 42 (82.4) | |
| ≥9.5 | 7 (7.8) | 4 (7.8) | |
| Lymphocyte count, ×10/L | |||
| Normal | 67 (74.4) | 39 (76.5) | NS |
| Reduced | 23 (25.6) | 12 (23.5) | |
| C-reactive protein (CRP) | |||
| Normal | 32 (35.6) | 15 (29.4) | NS |
| Increased | 58 (64.4) | 36 (70.6) | |
| NS – not significant. | |||