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17 June 2020: Clinical Research

Clinical and Demographic Characteristics of Cluster Cases and Sporadic Cases of Coronavirus Disease 2019 (COVID19) in 141 Patients in the Main District of Chongqing, China, Between January and February 2020

Peng Chen ABE* , Ying Zhang BCF* , Yongsheng Wen DE , Jinjun Guo BD , Weizhi Bai BCE , Jinwei Jia EF , Yu Ma ACG* , Yi Xu BDEG*

DOI: 10.12659/MSM.923985

Med Sci Monit 2020; 26:e923985

Table 3 The clinical characteristics of cluster and sporadic cases of coronavirus disease 2019 (COVID-19) in the main district of Chongqing, China, from January 25th to February 25th, 2020.

CharacteristicsCluster cases (N=90)Sporadic cases (N=51)P-value
Age (mean±SD) (years)50.1±8.242.0±7.70.01
Gender, n (%)
 Men43 (47.8)30 (58.8)NS
 Women47 (52.2)21 (41.2)
 Hypertension25 (27.8)9 (17.6)NS
 Diabetes18 (20.0)8 (15.7)NS
 Coronary heart disease14 (15.6)9 (17.6)NS
 Chronic obstructive pulmonary disease10 (11.1)7 (13.7)NS
Time from contact to illness8.3±3.27.1±3.8NS
Symptoms, n (%)
 Fever36 (40)31 (60.8)0.02
  37.3–38.025 (69.4)14 (45.2)0.04
  ≥38.011 (30.6)17 (54.8)
 Cough40 (44.4)29 (56.9)NS
 Fatigue9 (10)10 (19.6)NS
 Muscle ache9 (10)8 (15.7)NS
 Sore throat8 (8.9)6 (11.8)NS
 Headache8 (8.9)5 (9.8)NS
 Rhinorrhea7 (7.7)4 (7.8)NS
 Dyspnoea7 (7.8)7 (13.7)NS
 Nausea or vomiting6 (6.7)3 (6)NS
 Diarrhea3 (3.3)2 (3.9)NS
 Palpitations10 (11.1)6 (11.8)NS
 Asymptomatic29 (32.2)3 (5.9)0.00
Clinical classification
 Mild case41160.02
 Moderate case4425
 Severe case510
Radiology examination
 Bilateral lung involvement70 (77.8)41 (80.4)NS
 Typical chest CT manifestations66 (73.3)45 (88.2)0.04
Laboratory examination
 White blood cell count, ×10/L
  ≤3.512 (13.3)5 (9.8)NS
  3.5–9.571 (78.9)42 (82.4)
  ≥9.57 (7.8)4 (7.8)
 Lymphocyte count, ×10/L
  Normal67 (74.4)39 (76.5)NS
  Reduced23 (25.6)12 (23.5)
C-reactive protein (CRP)
 Normal32 (35.6)15 (29.4)NS
 Increased58 (64.4)36 (70.6)
NS – not significant.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750