29 June 2020 : Laboratory Research
Potential Molecular Mechanisms and Drugs for Aconitine-Induced Cardiotoxicity in Zebrafish through RNA Sequencing and Bioinformatics Analysis
Mingzhu Wang1CDEF, Yanan Shi1BDF, Lei Yao1CDF, Qiang Li2ACDFG, Youhua Wang3ABDFG, Deyu Fu1ABEFG*DOI: 10.12659/MSM.924092
Med Sci Monit 2020; 26:e924092
Table 1 Heart rates and SV-BA of zebrafish in each group at 72 hpf (n=16).
| Groups | Heart rates* (bpm) (χ̄±s) | SV-BA# (μm) (χ̄±s) |
|---|---|---|
| Control | 163.7±3.1 | 131.1±3.5 |
| AC 15 mg/L | 199.0±4.8 | 163.8±4.9 |
| −6.1 | −5.4 | |
| 0.000 | 0.000 | |
| There was a significant difference between the control group and the AC 15 mg/L group both in heart rates and SV-BA ( t=−6.1, | ||