02 July 2020 : Database Analysis
A Seven-Gene Signature with Close Immune Correlation Was Identified for Survival Prediction of Lung Adenocarcinoma
Xuan Zou1ABCDEF, Zhihuang Hu1AB, Changjing Huang1DF, Jianhua Chang1AG*DOI: 10.12659/MSM.924269
Med Sci Monit 2020; 26:e924269
Table 1 Demographic and clinical characteristics of subjects in the four datasets.
| Variables | TCGA-LUAD | GSE30219 | GSE41271 | GSE42127 |
|---|---|---|---|---|
| Gender | ||||
| Male | 232 (46.5%) | 65 (78.3%) | 90 (50.0%) | 66 (50.8%) |
| Female | 267 (53.5%) | 18 (21.7%) | 90 (50.0%) | 64 (49.2%) |
| Age | ||||
| <60 | 139 (27.9%) | 37 (44.6%) | 63 (35.0%) | 37 (28.5%) |
| ≥60 | 360 (72.1%) | 46 (55.4%) | 117 (65.0%) | 93 (71.5%) |
| TNM stage | ||||
| I | 273 (54.7%) | 79 (95.2%) | 97 (53.9%) | 87 (67.0%) |
| II | 115 (23.0%) | 2 (2.4%) | 29 (16.1%) | 22 (16.9%) |
| III | 78 (15.6%) | 2 (2.4%) | 49 (27.2%) | 19 (14.6%) |
| IV | 25 (5.0%) | 0 (0.0%) | 4 (2.2%) | 1 (0.8%) |
| Unknown | 8 (1.6%) | 0 (0.0%) | 1 (0.6%) | 1 (0.8%) |
| T (topography) | ||||
| T1 | 166 (33.3%) | 69 (83.1%) | – | – |
| T2 | 267 (53.5%) | 12 (14.5%) | – | – |
| T3 | 45 (9.0%) | 2 (2.4%) | – | – |
| T4 | 18 (3.6%) | 0 (0.0%) | – | – |
| Unknown | 3 (0.6%) | 0 (0.0%) | – | – |
| N (lymph node) | ||||
| N1 | 325 (65.1%) | 80 (96.4%) | – | – |
| N2 | 90 (18.0%) | 3 (3.6%) | – | – |
| N3 | 69 (13.8%) | 0 (0.0%) | – | – |
| Unknown | 15 (3.0%) | 0 (0.0%) | – | – |
| M (metastasis) | ||||
| M0 | 330 (66.1%) | 83 (100.0%) | – | – |
| M1 | 24 (4.8%) | 0 (0.0%) | – | – |
| Unknown | 145 (29.1%) | 0 (0.0%) | – | – |
| EGFR mutation | ||||
| (+) | 61 (12.2%) | 0 (0.0%) | – | – |
| (−) | 416 (83.4%) | 0 (0.0%) | – | – |
| Unknown | 22 (4.4%) | 83 (100.0%) | – | – |
| ALK mutation | ||||
| (+) | 31 (6.2%) | 0 (0.0%) | – | – |
| (−) | 446 (89.4%) | 0 (0.0%) | – | – |
| Unknown | 22 (4.4%) | 83 (100.0%) | – | – |
| KRAS mutation | ||||
| (+) | 115 (23.0%) | 0 (0.0%) | – | – |
| (−) | 362 (72.5%) | 0 (0.0%) | – | – |
| Unknown | 22 (4.4%) | 83 (100.0%) | – | – |