15 July 2020 : Clinical Research
Argatroban Increased the Basal Vein Drainage and Improved Outcomes in Acute Paraventricular Ischemic Stroke Patients
Shoufeng Liu12AE, Peipei Liu2BCDEF, Po Wang3BC, Fang Zhang4BD, Lijun Wang5BD, Yu Wang6BD, Hao Lu7B, Xiaofeng Ma4AG*DOI: 10.12659/MSM.924593
Med Sci Monit 2020; 26:e924593
Table 1 Characteristics of the patients at baseline.
| Characteristic | Control n=30 | Argatroban n=30 | p value |
|---|---|---|---|
| Age, y | 57.1±10.7 | 57.7±8.8 | 0.33 |
| Female sex, n (%) | 6 (20) | 7 (23) | 0.75 |
| Previous stroke, n (%) | 3 (10) | 2 (6) | 0.64 |
| Risk factors, n (%) | |||
| Hypertension | 17 (57) | 19 (63) | 0.60 |
| Heart disease | 2 (6) | 3 (10) | 0.64 |
| Hyperlipidemia | 5 (17) | 7 (23) | 0.52 |
| Smoking | 11 (37) | 13 (43) | 0.60 |
| Renal failure | 0 (0) | 0 (0) | 1.00 |
| Diabetes mellitus | 0 (0) | 0 (0) | 1.00 |
| Etiology*, n (%) | |||
| Subtype 1: atheromatosis | 30 (100) | 30 (100) | 1.00 |
| Subtype 2: embolus | 0 (0) | 0 (0) | 1.00 |
| Subtype 3: lacunar infarct | 0 (0) | 0 (0) | 1.00 |
| Subtype 4: other causes | 0 (0) | 0 (0) | 1.00 |
| Subtype 5: undetermined | 0 (0) | 0 (0) | 1.00 |
| INR | 1.0±0.1 | 1.0±0.1 | 0.69 |
| Infarct volume on admission, mL | 21.1±2.9 | 20.7±3.1 | 0.85 |
| NIHSS score at baseline, median(range) | 8 (5~12) | 8 (5~13) | 0.58 |
| Time to treatment, h | 26±8 | 25±10 | 0.36 |
| Plus-minus values are mean±SE. a Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. INR – international normalized ratio; NIHSS – National Institutes of Health Stroke Scale. | |||