Effects of Jian-Pi-Zhi-Dong Decoction on the Expression of 5-HT and Its Receptor in a Rat Model of Tourette Syndrome and Comorbid Anxiety

01 August 2020: Animal Study

Dan Wang ^1BE , Hui-ling Tian ^2CF , Xia Cui ^3DG , Qian Wang ^3C , Fan Guo ^3BC , Wen Zhang ^3ABCDEFG* , Qi-sheng Tang ^1AG*

DOI: 10.12659/MSM.924658

Med Sci Monit 2020; 26:e924658

Table 1 A randomized regimen of water feeding in the Tourette syndrome and comorbid anxiety rat model stimulated by an empty bottle.

Time	8: 00–8: 10	20: 00–20: 10	Time	8: 00–8: 10	20: 00–20: 10
Day 1	Water	Water	Day 12	Water	Empty bottle
Day 2	Water	Water	Day 13	Water	Empty bottle
Day 3	Water	Water	Day 14	Water	Empty bottle
Day 4	Water	Water	Day 15	Water	Empty bottle
Day 5	Water	Water	Day 16	Empty bottle	Water
Day 6	Water	Water	Day 17	Water	Empty bottle
Day 7	Water	Water	Day 18	Empty bottle	Water
Day 8	Empty bottle	Water	Day 19	Empty bottle	Water
Day 9	Water	Empty bottle	Day 20	Empty bottle	Water
Day 10	Water	Empty bottle	Day 21	Water	Empty bottle
Day 11	Empty bottle	Water