09 August 2020: Lab/In Vitro Research
Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1α (HIF-1α) Expression
Xiaoxu Fang 1B* , Dandan Zhang 2CD* , Wei Zhao 3CD , Longfei Gao 4DE , Lanping Wang 5ABCDEF*DOI: 10.12659/MSM.924670
Med Sci Monit 2020; 26:e924670
Table 2 Relationship between 5-year OS and clinical factors.
| Factor | 5-year OS (%) | P* |
|---|---|---|
| Sex | ||
| Female | 26.5 | 0.585 |
| Male | 29.0 | |
| Age | ||
| 29.6 | 0.754 | |
| ≥50 | 28.4 | |
| Tumor size (cm) | ||
| ≤5 | 41.9 | 0.001 |
| >5 | 21.3 | |
| Tumor number | ||
| Single | 27.7 | 0.732 |
| Multiple | 40.0 | |
| Histopathological grade | ||
| I+II | 28.4 | 0.951 |
| III | 33.3 | |
| HBsAg | ||
| Negative | 40.7 | 0.280 |
| Positive | 23.1 | |
| HCV | ||
| Negative | 28.9 | 0.302 |
| Positive | 30.0 | |
| Cirrhosis | ||
| Negative | 34.0 | 0.798 |
| Positive | 25.6 | |
| Microvascular invasion | ||
| Negative | 34.3 | 0.531 |
| Positive | 28.2 | |
| T stage | ||
| I+II | 43.7 | |
| III+IV | 16.2 | |
| N stage | ||
| N0 | 29.4 | 0.280 |
| N1 | 0.0 | |
| TNM stage | ||
| I+II | 43.7 | |
| III+IV | 16.2 | |
| DAAM1 | ||
| Low | 26.3 | 0.907 |
| High | 36.4 | |
| DAAM2 | ||
| Low | 38.5 | 0.004 |
| High | 18.8 | |
| HCV – hepatitis C virus. | ||