09 August 2020 : Clinical Research
Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1α (HIF-1α) Expression
Xiaoxu Fang1B, Dandan Zhang2CD, Wei Zhao3CD, Longfei Gao4DE, Lanping Wang5ABCDEF*DOI: 10.12659/MSM.924670
Med Sci Monit 2020; 26:e924670
Related articles
16 Aug 2022 : Clinical Research
Hemoglobin/Red Blood Cell Distribution Width Ratio in Peripheral Blood Is Positively Associated with Prognosis of Patients with Primary Hepatocellular Carcinoma
Yue Fang, Xiaonan Sun
DOI: 10.12659/MSM.937146
Med Sci Monit 2022; 28:e937146
21 Jul 2022 : Clinical Research
Serum T Cell Immunoglobulin Mucin 3 Predicts Worse Prognosis in Hepatocellular Carcinoma Patients Undergoing Transcatheter Arterial Chemoembolization
Jun Li, Jing Wang
DOI: 10.12659/MSM.935326
Med Sci Monit 2022; 28:e935326
13 Dec 2021 : Database Analysis
Integrated Analysis of Angiogenesis-Mediated Tumor Immune Microenvironment Pattern in Hepatocellular Carcinoma (HCC) and a Novel Prognostic Model Construction to Predict Patient Outcome
Chengqian Lv, Qianqian Huang
DOI: 10.12659/MSM.934937
Med Sci Monit 2021; 27:e934937
25 Oct 2021 : Database Analysis
RNA N6-Methyladenosine Patterns in Hepatocellular Carcinoma Reveal a Distinct Immune Infiltration Landscape and Clinical Significance
Hua Zhao, Qiujun Zhou
DOI: 10.12659/MSM.930994
Med Sci Monit 2021; 27:e930994
31 Mar 2021 : Laboratory Research
Connection Between CDC20 Expression and Hepatocellular Carcinoma Prognosis
Xianfeng Zhang, Xianjun Zhang
DOI: 10.12659/MSM.926760
Med Sci Monit 2021; 27:e926760
13 Jan 2020 : Clinical Research
The Prognostic Role of a Combined Fibrinogen and Neutrophil-to-Lymphocyte Ratio Score in Patients with Resectable Hepatocellular Carcinoma: A Retrospective Study
Weihao Kong, Honghai Xu
DOI: 10.12659/MSM.918824
Med Sci Monit 2020; 26:e918824
09 Mar 2020 : Database Analysis
Overexpression of Karyopherin Subunit alpha 2 (KPNA2) Predicts Unfavorable Prognosis and Promotes Bladder Cancer Tumorigenicity via the P53 Pathway
Changlong Shi, Li Sun
DOI: 10.12659/MSM.921087
Med Sci Monit 2020; 26:e921087
19 Jan 2020 : Laboratory Research
MicroRNA-639 is Down-Regulated in Hepatocellular Carcinoma Tumor Tissue and Inhibits Proliferation and Migration of Human Hepatocellular Carcinoma Cells Through the KAT7/Wnt/β-Catenin Pathway
Zhijie Bai, Xiaopu Xia
DOI: 10.12659/MSM.919241
Med Sci Monit 2020; 26:e919241
23 Jan 2020 : Clinical Research
Development and Identification of a Nomogram Prognostic Model for Patients with Primary Clear Cell Carcinoma of the Liver
Ziying Zhang, Hui Xie
DOI: 10.12659/MSM.919789
Med Sci Monit 2020; 26:e919789
24 Feb 2020 : Clinical Research
Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) Acts as Diagnostic Biomarker and Adverse Prognostic Factor of Hepatocellular Carcinoma (HCC): Evidence from Bioinformatic Analysis
Wensheng Wang, Guangxi Zhu
DOI: 10.12659/MSM.919896
Med Sci Monit 2020; 26:e919896
19 Feb 2020 : Laboratory Research
miRNA-411 Regulates Chondrocyte Autophagy in Osteoarthritis by Targeting Hypoxia-Inducible Factor 1 alpha (HIF-1α)
Fei Yang, Rong Huang
DOI: 10.12659/MSM.921155
Med Sci Monit 2020; 26:e921155
31 May 2020 : Clinical Research
An Individualized Immune Prognostic Index is a Superior Predictor of Survival of Hepatocellular Carcinoma
Xiaodong Wang, Yuquan Wu
DOI: 10.12659/MSM.921786
Med Sci Monit 2020; 26:e921786
30 May 2020 : Laboratory Research
Hirudin Reduces the Expression of Markers of the Extracellular Matrix in Renal Tubular Epithelial Cells in a Rat Model of Diabetic Kidney Disease Through the Hypoxia-Inducible Factor-1α (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway
Xinxin Pang, Yage Zhang
DOI: 10.12659/MSM.921894
Med Sci Monit 2020; 26:e921894
31 Mar 2020 : Database Analysis
Bioinformatics Analysis of Prognostic Tumor Microenvironment-Related Genes in the Tumor Microenvironment of Hepatocellular Carcinoma
Zongbiao Tian, Zheng Wang
DOI: 10.12659/MSM.922159
Med Sci Monit 2020; 26:e922159
23 Jun 2020 : Clinical Research
The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis
Mei Tian, Xiuchun Yang
DOI: 10.12659/MSM.923359
Med Sci Monit 2020; 26:e923359
18 Sep 2020 : Database Analysis
Development and Validation of a Novel Immune-Gene Pairs Prognostic Model Associated with CTNNB1 Alteration in Hepatocellular Carcinoma
Junyu Huo, Liqun Wu
DOI: 10.12659/MSM.925494
Med Sci Monit 2020; 26:e925494
16 Oct 2020 : Clinical Research
Single Large Nodule (>5 cm) Prognosis in Hepatocellular Carcinoma: Kinship with Barcelona Clinic Liver Cancer (BCLC) Stage A or B?
Li Wan, Ding-Hui Dong
DOI: 10.12659/MSM.926797
Med Sci Monit 2020; 26:e926797
11 Aug 2020 : Review article
Current Status of Research on the Role of Circular RNAs in Hepatocellular Carcinoma and Clinical Implications
Ren-Chao Zou, Ling-Lin Li
DOI: 10.12659/MSM.923832
Med Sci Monit 2020; 26:e923832
14 Nov 2019 : Clinical Research
Comparison of Imaging and Clinically Relevant Features of Combined Hepatocellular Carcinoma and Cholangiocarcinoma with Hepatocellular Carcinoma
Xialing Huang, Yajuan Li
DOI: 10.12659/MSM.917418
Med Sci Monit 2019; 25:8595-8601
25 May 2019 : Clinical Research
Clinical Significance of TRMT6 in Hepatocellular Carcinoma: A Bioinformatics-Based Study
Yang Wang, Qiao Huang
DOI: 10.12659/MSM.913556
Med Sci Monit 2019; 25:3894-3901
05 Sep 2019 : Clinical Research
Thyroid Receptor-Interacting Protein 13 is Correlated with Progression and Poor Prognosis in Bladder Cancer
Lijuan Niu, Zhiqiang Gao
DOI: 10.12659/MSM.917112
Med Sci Monit 2019; 25:6660-6668
30 Apr 2019 : Laboratory Research
Butyrophilin-Like 9 (BTNL9) Suppresses Invasion and Correlates with Favorable Prognosis of Uveal Melanoma
Zhongming Jiang, Fei Liu
DOI: 10.12659/MSM.914074
Med Sci Monit 2019; 25:3190-3198
27 Apr 2019 : Animal Research
Effects of Sevoflurane Pretreatment on Myocardial Ischemia-Reperfusion Injury Through the Akt/Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway
Jingwei Dong, Mingjun Xu
DOI: 10.12659/MSM.914265
Med Sci Monit 2019; 25:3100-3107
04 Apr 2019 : Laboratory Research
Genome-Wide Association Study Identifies a Genetic Prediction Model for Postoperative Survival in Patients with Hepatocellular Carcinoma
Jinwang Wei, Yuanyuan Sheng
DOI: 10.12659/MSM.915511
Med Sci Monit 2019; 25:2452-2478
20 Mar 2019 : Clinical Research
Long Noncoding RNA (lncRNA) Small Nucleolar RNA Host Gene 16 (SNHG16) Predicts Poor Prognosis and Sorafenib Resistance in Hepatocellular Carcinoma
Zhenli Guo, Ju Zhang
DOI: 10.12659/MSM.915541
Med Sci Monit 2019; 25:2079-2086
01 Apr 2019 : Clinical Research
High-Mobility Group Box 1 (HMGB1) Promotes Angiogenesis and Tumor Migration by Regulating Hypoxia-Inducible Factor 1 (HIF-1α) Expression via the Phosphatidylinositol 3-Kinase (PI3K)/AKT Signaling Pathway in Breast Cancer Cells
Honger He, Xingmu Wang
DOI: 10.12659/MSM.915690
Med Sci Monit 2019; 25:2352-2360
03 Sep 2019 : Review article
Non-Cirrhotic Liver is Associated with Poor Prognosis of Hepatocellular Carcinoma: A Literature Review
Yan Liu, Hao Li
DOI: 10.12659/MSM.915722
Med Sci Monit 2019; 25:6615-6623
08 Jun 2019 : Laboratory Research
Knockdown of Hypoxia-Inducible Factor 1α (HIF-1α) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells
Jinling Huang, Likun Gao
DOI: 10.12659/MSM.915730
Med Sci Monit 2019; 25:4250-4263
05 Aug 2019 : Clinical Research
Increased Expression of Serine Hydroxymethyltransferase 2 (SHMT2) is a Negative Prognostic Marker in Patients with Hepatocellular Carcinoma and is Associated with Proliferation of HepG2 Cells
Lijuan Ji, Yuanyuan Tang
DOI: 10.12659/MSM.915754
Med Sci Monit 2019; 25:5823-5832
20 May 2019 : Clinical Research
Expression of WD Repeat Domain 5 (WDR5) is Associated with Progression and Reduced Prognosis in Papillary Thyroid Carcinoma
Wenchao Xu, Lingling Wang
DOI: 10.12659/MSM.915847
Med Sci Monit 2019; 25:3762-3770
11 Oct 2019 : Laboratory Research
Long Non-Coding RNAs (lncRNAs) Tumor-Suppressive Role of lncRNA on Chromosome 8p12 (TSLNC8) Inhibits Tumor Metastasis and Promotes Apoptosis by Regulating Interleukin 6 (IL-6)/Signal Transducer and Activator of Transcription 3 (STAT3)/Hypoxia-Inducible Factor 1-alpha (HIF-1α) Signaling Pathway in Non-Small Cell Lung Cancer
Hanli Fan, Jianbo Li
DOI: 10.12659/MSM.917565
Med Sci Monit 2019; 25:7624-7633
19 Aug 2019 : Clinical Research
Decreased Expression of Long Non-Coding RNA GMDS Divergent Transcript (GMDS-DT) is a Potential Biomarker for Poor Prognosis of Hepatocellular Carcinoma
Duo Wang, Xiufang Du
DOI: 10.12659/MSM.917663
Med Sci Monit 2019; 25:6221-6229
18 Oct 2019 : Clinical Research
Expression of Rho Guanine Nucleotide Exchange Factor 39 (ARHGEF39) and Its Prognostic Significance in Hepatocellular Carcinoma
Jian Gao, Wei-Dong Jia
DOI: 10.12659/MSM.918270
Med Sci Monit 2019; 25:7826-7835
25 Sep 2019 : Laboratory Research
Hypoxia-Inducible Factor-1α (HIF-1α) Promotes Hypoxia-Induced Invasion and Metastasis in Ovarian Cancer by Targeting Matrix Metallopeptidase 13 (MMP13)
Hui Zhang, Qingju Yang
DOI: 10.12659/MSM.916886
Med Sci Monit 2019; 25:7202-7208
27 Dec 2019 : Laboratory Research
miR-206 Inhibits Cell Proliferation and Extracellular Matrix Accumulation by Targeting Hypoxia-Inducible Factor 1-alpha (HIF-1α) in Mesangial Cells Treated with High Glucose
Yanchao Cao, Xufen Cao
DOI: 10.12659/MSM.918912
Med Sci Monit 2019; 25:10036-10044
31 Aug 2019 : Clinical Research
Upregulation of Long Non-Coding RNA ENST00000429227.1 Is Correlated with Poor Prognosis in Human Hepatocellular Carcinoma
Yuan Zhao, Cun-Qing Kong
DOI: 10.12659/MSM.916551
Med Sci Monit 2019; 25:6539-6546
31 Jul 2019 : Clinical Research
Prognostic Significance of Increased Expression of Annexin A10 (ANXA10) in Serous Epithelial Ovarian Cancer
Jing Wang, Shanshan Zhao
DOI: 10.12659/MSM.915911
Med Sci Monit 2019; 25:5666-5673
08 Dec 2018 : Animal Research
Hypoxia-Inducible Factor 1 alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Pathway Participates in Angiogenesis of Myocardial Infarction in Muscone-Treated Mice: Preliminary Study
Yingqiang Du, Yingbin Ge
DOI: 10.12659/MSM.912051
Med Sci Monit 2018; 24: ANS8870-8877
11 Dec 2018 : Laboratory Research
Resveratrol Induces Apoptosis in Murine Prostate Cancer Cells via Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Reactive Oxygen Species (ROS)/P53 Signaling
Delong Wang, Zefeng Gao
DOI: 10.12659/MSM.913290
Med Sci Monit 2018; 24: LBR8970-8976
03 Dec 2018 : Laboratory Research
Hypoxia-Inducible Factor 1-α (HIF-1α) Induces Apoptosis of Human Uterosacral Ligament Fibroblasts Through the Death Receptor and Mitochondrial Pathways
Xinrui Zhao, Lidong Liu
DOI: 10.12659/MSM.913384
Med Sci Monit 2018; 24: LBR8722-8733
20 Mar 2018 : Clinical Research
Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells
Kaishun Shi, Qingjing Ru
DOI: 10.12659/MSM.906075
Med Sci Monit 2018; 24: CLR1642-1653
09 Dec 2018 : Clinical Research
High Mobility Group Box 1 (HMGB1) Predicts Invasion and Poor Prognosis of Glioblastoma Multiforme via Activating AKT Signaling in an Autocrine Pathway
Peng Cheng, Yun Ma
DOI: 10.12659/MSM.912104
Med Sci Monit 2018; 24: CLR8916-8924
23 Oct 2018 : Clinical Research
High Expression of PTPN3 Predicts Progression and Unfavorable Prognosis of Glioblastoma
Yu Wang, Yan Su
DOI: 10.12659/MSM.911531
Med Sci Monit 2018; 24: CLR7556-7562
29 Aug 2018 : Laboratory Research
Sperm-Associated Antigen 5 Expression Is Increased in Hepatocellular Carcinoma and Indicates Poor Prognosis
Hua Zhou, Shun-cai Wang
DOI: 10.12659/MSM.911434
Med Sci Monit 2018; 24: LBR6021-6028
09 Nov 2018 : Clinical Research
TRIM15 Exerts Anti-Tumor Effects Through Suppressing Cancer Cell Invasion in Gastric Adenocarcinoma
Weilin Chen, Chuanhui Lu
DOI: 10.12659/MSM.911142
Med Sci Monit 2018; 24: CLR8033-8041
09 Oct 2018 : Clinical Research
EphA8 is a Prognostic Factor for Oral Tongue Squamous Cell Carcinoma
Lijun Liu, Xiaofeng Wang
DOI: 10.12659/MSM.910909
Med Sci Monit 2018; 24: CLR7213-7222
24 Oct 2018 : Laboratory Research
Increased Expression of Lysine-Specific Demethylase 5B (KDM5B) Promotes Tumor Cell Growth in Hep3B Cells and is an Independent Prognostic Factor in Patients with Hepatocellular Carcinoma
Jian Gong, Shuyuan Yan
DOI: 10.12659/MSM.910844
Med Sci Monit 2018; 24: LBR7586-7594
19 Oct 2018 : Laboratory Research
Silencing BRIT1 Facilitates the Abilities of Invasiveness and Migration in Trophoblast Cells
Luping Liu, Li Sun
DOI: 10.12659/MSM.910229
Med Sci Monit 2018; 24: LBR7451-7458
19 Sep 2018 : Laboratory Research
Elevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/β-Catenin Signaling Pathway
Yibin Wu, Wenjie Chen
DOI: 10.12659/MSM.910105
Med Sci Monit 2018; 24: LBR6608-6616
25 Mar 2018 : Clinical Research
Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms
Xujing Wang, Qiqi Zhang
DOI: 10.12659/MSM.909368
Med Sci Monit 2018; 24: CLR1742-1750
16 Jul 2018 : Clinical Research
High Expression of Ubiquitin-Specific Protease 8 (USP8) Is Associated with Poor Prognosis in Patients with Cervical Squamous Cell Carcinoma
Min Yan, Cuihong Zhao
DOI: 10.12659/MSM.909235
Med Sci Monit 2018; 24: CLR4934-4943
26 Mar 2018 : Clinical Research
MAP Kinase-Interacting Kinase 1 Promotes Proliferation and Invasion of Hepatocellular Carcinoma and Is an Unfavorable Prognostic Biomarker
Xujing Wang, Yongkun Wang
DOI: 10.12659/MSM.909012
Med Sci Monit 2018; 24: CLR1759-1767
26 May 2018 : Clinical Research
Reduced Expression of Deubiquitinase USP33 Is Associated with Tumor Progression and Poor Prognosis of Gastric Adenocarcinoma
Yan Chen, Xumei Pang
DOI: 10.12659/MSM.908075
Med Sci Monit 2018; 24: CLR3496-3505
27 Apr 2018 : Laboratory Research
Quercetin Inhibits the Migration and Invasion of HCCLM3 Cells by Suppressing the Expression of p-Akt1, Matrix Metalloproteinase (MMP) MMP-2, and MMP-9
Jun Lu, Zhiqiang Wang
DOI: 10.12659/MSM.906172
Med Sci Monit 2018; 24: LBR2583-2589
01 May 2017 : Laboratory Research
Expression and Correlation of Hypoxia-Inducible Factor-1α (HIF-1α) with Pulmonary Artery Remodeling and Right Ventricular Hypertrophy in Experimental Pulmonary Embolism
Wenjuan Liu, Yimei Zhang
DOI: 10.12659/MSM.900354
Med Sci Monit 2017; 23:2083-2088
31 Oct 2014 : Hypothesis
Blocking HIF-1α Following Radiotherapy to Prolong and Enhance the Immune Effects of Radiotherapy: A Hypothesis
Luo Wei, Ge Wei
DOI: 10.12659/MSM.891048
Med Sci Monit 2014; 20:2106-2108
Editorial
01 February 2025 : Editorial
Editorial: Current Approaches to Screening for Lung Cancer in Smokers and Non-SmokersDOI: 10.12659/MSM.948255
Med Sci Monit 2025; 31:e948255
In Press
Clinical Research
Correlation Descriptive Study on Nurses' Professional Values and Job Satisfaction and the Ethical Climate o...Med Sci Monit In Press; DOI: 10.12659/MSM.945639
Clinical Research
Pre- and Post-Surgical MRI Analysis of Levator Ani in Pelvic Organ Prolapse Patients: A Single-Center StudyMed Sci Monit In Press; DOI: 10.12659/MSM.945993
Clinical Research
Comparative Impact of Kinesio Taping and Post-Isometric Muscle Relaxation on Pain and Myofascial Mechanics ...Med Sci Monit In Press; DOI: 10.12659/MSM.945376
Clinical Research
Surgical Efficacy in Varicocele Ligation with Ephedrine-Assisted Blood Pressure ControlMed Sci Monit In Press; DOI: 10.12659/MSM.946234
Most Viewed Current Articles
17 Jan 2024 : Review article 6,968,210
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research 701,772
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Mar 2024 : Editorial 25,357
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and ...DOI :10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
28 Jan 2024 : Review article 19,972
A Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and FutureDOI :10.12659/MSM.943912
Med Sci Monit 2024; 30:e943912