Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1α (HIF-1α) Expression

09 August 2020: Lab/In Vitro Research

Xiaoxu Fang ^1B* , Dandan Zhang ^2CD* , Wei Zhao ^3CD , Longfei Gao ^4DE , Lanping Wang ^5ABCDEF*

DOI: 10.12659/MSM.924670

Med Sci Monit 2020; 26:e924670

Table 4 Relationship between DAAM2 and clinical factors.

Factors	DAAM2		P*
Factors	Low	High	P*
Sex
Female	14	23	0.047
Male	46	34
Age
	25	21	0.705
≥50	35	36
Tumor size (cm)
≤5	28	17	0.087
>5	32	40
Tumor number
Single	55	52	0.932
Multiple	5	5
Histopathological grade
I+II	44	40	0.837
III	16	17
HBsAg
Negative	19	17	0.844
Positive	41	40
HCV
Negative	57	50	0.197
Positive	3	7
Microvascular invasion
Negative	24	30	0.392
Positive	33	30
Cirrhosis
Negative	35	28	0.357
Positive	25	29
T stage
I+II	35	22	0.032
III+IV	25	35
N stage
N0	59	56	0.971
N1	1	1
TNM stage
I+II	35	22	0.032
III+IV	25	35
DAAM1
Low	48	47	0.815
High	12	10
^* Calculated by the Chi-square test. HBsAg – hepatitis B surface antien; HCV – hepatitis C virus.