02 September 2020 : Database Analysis
A Novel Risk Model Based on Autophagy Pathway Related Genes for Survival Prediction in Lung Adenocarcinoma
Fan Zhang1ABCG, Suzhen Xie1DE, Zhenyu Zhang1C, Huanhuan Zhao1E, Zijun Zhao1F, Haiying Sun2G, Jiao Zheng1A*DOI: 10.12659/MSM.924710
Med Sci Monit 2020; 26:e924710
Table 2 Characteristics of risk APRGs in the prognostic model.
| Gene | Univariate analysis | Co-efficient | Multivariate analysis | ||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| CCR2 | 0.7892 (0.6648–0.9369) | 0.0069 | −0.2807 | 0.7553 (0.6269–0.9098) | 0.0031 |
| LAMP1 | 1.0006 (1.0012–0.04949) | 0.0008 | 0.0008 | 1.0008 (1.0002–1.0014) | 0.0119 |
| RELA | 1.0545 (1.0101–1.1010) | 0.0157 | 0.0466 | 1.0477 (1.0047–1.0925) | 0.0295 |
| ATG12 | 1.1781 (1.0077–1.3773) | 0.0398 | 0.2662 | 1.3049 (1.1039–1.5426) | 0.0018 |
| MBTPS2 | 1.2306 (1.0652–1.4217) | 0.0048 | 0.1513 | 1.1634 (1.0075–1.3434) | 0.0393 |
| ATG9A | 1.1129 (1.0298–1.2027) | 0.0069 | |||
| NCKAP1 | 1.0705 (1.0064–1.1387) | 0.0306 | |||
| ATG10 | 1.4181 (1.0128–1.9856) | 0.0420 | |||
| DNAJB9 | 0.9758 (0.9524–0.9997) | 0.0474 | |||
| APRGs – autophagy-pathway-related genes; HR – hazard ratio; CI – confidence interval. | |||||