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02 September 2020: Database Analysis

A Novel Risk Model Based on Autophagy Pathway Related Genes for Survival Prediction in Lung Adenocarcinoma

Fan Zhang 1ABCG , Suzhen Xie 1DE , Zhenyu Zhang 1C , Huanhuan Zhao 1E , Zijun Zhao 1F , Haiying Sun 2G* , Jiao Zheng 1A*

DOI: 10.12659/MSM.924710

Med Sci Monit 2020; 26:e924710

Table 2 Characteristics of risk APRGs in the prognostic model.

GeneUnivariate analysisCo-efficientMultivariate analysis
HR (95% CI)P valueHR (95% CI)P value
CCR20.7892 (0.6648–0.9369)0.0069−0.28070.7553 (0.6269–0.9098)0.0031
LAMP11.0006 (1.0012–0.04949)0.00080.00081.0008 (1.0002–1.0014)0.0119
RELA1.0545 (1.0101–1.1010)0.01570.04661.0477 (1.0047–1.0925)0.0295
ATG121.1781 (1.0077–1.3773)0.03980.26621.3049 (1.1039–1.5426)0.0018
MBTPS21.2306 (1.0652–1.4217)0.00480.15131.1634 (1.0075–1.3434)0.0393
ATG9A1.1129 (1.0298–1.2027)0.0069
NCKAP11.0705 (1.0064–1.1387)0.0306
ATG101.4181 (1.0128–1.9856)0.0420
DNAJB90.9758 (0.9524–0.9997)0.0474
APRGs – autophagy-pathway-related genes; HR – hazard ratio; CI – confidence interval.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750