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12 November 2020: Animal Study

Effects of Vitamin D3 on Intestinal Flora in a Mouse Model of Inflammatory Bowel Disease Treated with Rifaximin

Zijun Gu 1BCDE , Mingxiu Duan 2BCD , Yan Sun 1BC , Tian Leng 1BC , Ting Xu 1BC , Yang Gu 1ABE , Zejuan Gu 13CD , Zheng Lin 13AF* , Lu Yang 1EF* , Minghui Ji 1ACEG*

DOI: 10.12659/MSM.925068

Med Sci Monit 2020; 26:e925068

Table 2 Community analysis pie-plot on genus level. DSS: Dextran sulfate sodium; VD3: Vitamin D3.

Intestinal flora\ControlDSSDSS+RifaximinDSS+Rifaximin+VD3
norank_f__Bacteroidales_S24-7: 41.28%Helicobacter: 16.70%norank_f__Bacteroidales_S24-7: 25.17%norank_f__Bacteroidales_S24-7: 36.60%
Lachnospiraceae_NK4A136: 9.93%norank_f__Bacteroides_S24-7: 11.26%Erysipelatoclostridium: 14.85%Bacteroides: 24.56%
Proteobacteria: 2.69%Escherichia-Shigella: 11.23%Morganella: 11.40%Escherichia-Shigella: 10.93%
Rikenellaceae_RC9_gut: 7.48%Bacteroides: 10.84%Bacteroides: 7.69%Erysipelato clostridium: 6.05%
Alistipes: 6.42%Turicibacter: 8.91%Helicobacter: 5.18%Parasutterella: 5.77%
Alloprevotella: 3.53%Mucispirillum: 4.73%Escherichia-Shigella: 4.37%Akkermansia: 4.28%
Bacteroides: 3.38%Lachnospiraceae_NK4A136: 3.93%Akkermansia: 4.04%Desulfo vibrio: 1.66%
Prevotellaceae_NK3B31: 2.38%Desulfo vibrio: 2.50%Parasutterella: 3.87%Morganella: 1.66%
Ruminococcaceae_UCG-014: 1.96%Morganella: 2.20%Rikenellaceae_RC9_gut: 2.82%norank_f_Rhodospirillaceae: 1.24%
norank_f_Lachnospiraceae: 1.72%,Enterococcus: 1.97%Proteus: 2.71%Lachnospiraceae_NK4A136_group: 1.10%

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750