23 December 2020: Clinical Research
A Real-World Study of Cerebral 99mTc-TRODAT-1 Single-Photon Emission Computed Tomography (SPECT) Imaging of the Dopamine Transporter in Patients with Parkinson Disease from a Tertiary Hospital in Brazil
Michelly Arjona 1CDEF* , Juliana M.P. Toldo 1BCDEF* , Natalia Carvalho Queiroz 1ABCD* , Jose Luiz Pedroso 2ACD* , Guilherme de Carvalho Campos Neto 2ACD* , Orlando G.P. Barsottini 2ACD* , Andre C. Felicio 1ABCDEF**DOI: 10.12659/MSM.925130
Med Sci Monit 2020; 26:e925130
Table 2 Patient demographics and clinical data.
| Total (N=119) | Movement disorder specialist dopamine transporter imaging request | p-Value | ||
|---|---|---|---|---|
| Yes (n=75) | No (n=44) | |||
| Gender | >0.999 | |||
| Male | 72 (61) | 45 (60) | 27 (62) | |
| Age (years) | 0.644 | |||
| Median [IIQ] | 67 [57; 73] | 66 [57; 71] | 68 [57; 73] | |
| Disease duration (years) | ||||
| Median [IIQ] | 4 [2; 6] | 4,8 [3; 6] | 3 [2; 6] | 0.031 |
| Symptoms | ||||
| Bradykinesia | 81 (68) | 51 (68) | 30 (68) | >0.999 |
| Tremor | 79 (66) | 46 (61) | 33 (75) | 0.186 |
| Rigidity | 60 (50) | 33 (44) | 27 (61) | 0.101 |
| Gait impairment | 37 (31) | 22 (29) | 15 (34) | 0.737 |
| Post. instability | 30 (25) | 15 (20) | 15 (34) | 0.136 |
| Depression | 25 (21) | 16 (21) | 9 (20) | >0.999 |
| Dystonia | 6 (5) | 5 (7) | 1 (2) | 0.411 |
| Others | 29 (24) | 16 (21) | 13 (29) | 0.432 |
| Categorical measures described in absolute value and, in parentheses, percentage. p-value for Fisher exact, Chi-square and Mann-Whitney tests. | ||||