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23 December 2020: Clinical Research

A Real-World Study of Cerebral 99mTc-TRODAT-1 Single-Photon Emission Computed Tomography (SPECT) Imaging of the Dopamine Transporter in Patients with Parkinson Disease from a Tertiary Hospital in Brazil

Michelly Arjona 1CDEF* , Juliana M.P. Toldo 1BCDEF* , Natalia Carvalho Queiroz 1ABCD* , Jose Luiz Pedroso 2ACD* , Guilherme de Carvalho Campos Neto 2ACD* , Orlando G.P. Barsottini 2ACD* , Andre C. Felicio 1ABCDEF**

DOI: 10.12659/MSM.925130

Med Sci Monit 2020; 26:e925130

Table 3 Brain scintigraphy with 99m Tc-TRODAT-1 requests and its clinical usefulness.

Dopamine transporter imaging indicationScan usefulness
Yes (n=101)No (n=18)
Evaluation/confirmation dopaminergic cell loss67 (82)15 (18)
Degenerative parkinsonism versus tremor essential12 (100)0 (0)
Degenerative parkinsonism versus drug-induced7 (100)0 (0)
Degenerative parkinsonism versus vascular3 (100)0 (0)
Parkinson’s disease versus atypical parkinsonism4 (67)2 (33)
Lewy body dementia versus Alzheimer1 (100)0 (0)
Degenerative parkinsonism versus hydrocephalus* 1 (100)0 (0)
Atypical tremor4 (100)0 (0)
Degenerative parkinsonism versus other mixed causes (hypoxia, encephalopathy, dystonia, ataxia, inflammation, etc.)2 (67)1 (33)
Data is presented in absolute values and, in parentheses, percentage.
* Normal pressure hydrocephalus.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750