23 December 2020 : Clinical Research
A Real-World Study of Cerebral 99mTc-TRODAT-1 Single-Photon Emission Computed Tomography (SPECT) Imaging of the Dopamine Transporter in Patients with Parkinson Disease from a Tertiary Hospital in Brazil
Michelly Arjona1CDEF, Juliana M.P. Toldo1BCDEF, Natalia Carvalho Queiroz1ABCD, Jose Luiz Pedroso2ACD, Guilherme de Carvalho Campos Neto2ACD, Orlando G.P. Barsottini2ACD, Andre C. Felicio1ABCDEF*DOI: 10.12659/MSM.925130
Med Sci Monit 2020; 26:e925130
Table 3 Brain scintigraphy with 99m Tc-TRODAT-1 requests and its clinical usefulness.
| Dopamine transporter imaging indication | Scan usefulness | |
|---|---|---|
| Yes (n=101) | No (n=18) | |
| Evaluation/confirmation dopaminergic cell loss | 67 (82) | 15 (18) |
| Degenerative parkinsonism versus tremor essential | 12 (100) | 0 (0) |
| Degenerative parkinsonism versus drug-induced | 7 (100) | 0 (0) |
| Degenerative parkinsonism versus vascular | 3 (100) | 0 (0) |
| Parkinson’s disease versus atypical parkinsonism | 4 (67) | 2 (33) |
| Lewy body dementia versus Alzheimer | 1 (100) | 0 (0) |
| Degenerative parkinsonism versus hydrocephalus* | 1 (100) | 0 (0) |
| Atypical tremor | 4 (100) | 0 (0) |
| Degenerative parkinsonism versus other mixed causes (hypoxia, encephalopathy, dystonia, ataxia, inflammation, etc.) | 2 (67) | 1 (33) |
| Data is presented in absolute values and, in parentheses, percentage. * Normal pressure hydrocephalus. | ||