Nomogram for Predicting Breast Cancer-Specific Mortality of Elderly Women with Breast Cancer

13 September 2020 : Database Analysis

Xunxi Lu^12ABCDEF, Xiaoguang Li^1ADEFG, Hong Ling^12DFG, Yue Gong^12ACD, Linwei Guo^12ACE, Min He^12DF, Hefen Sun^12DG, Xin Hu^12EFG*

DOI: 10.12659/MSM.925210

Med Sci Monit 2020; 26:e925210

Related articles Order reprints Share article Share by email

View HTML version

Table 3 Proportional subdistribution hazard model of probabilities of BCSD for patients in the training cohort.

Characteristics	Coefficient	sdHR (95% CI)	P-value
Age
65–74	Reference
75+	0.360	1.43 (1.30–1.58)	<0.001
Marriage
Unmarried	Reference
Married	−0.314	0.73 (0.65–0.82)	<0.001
Race
White	Reference
Black	0.482	1.62 (1.38–1.90)	<0.001
Other^*	−0.108	0.90 (0.74–1.09)	0.280
Histology
IDC	Reference
ILC	0.100	1.11 (0.94–1.29)	0.210
Other^**	−0.332	0.72 (0.63–0.82)	<0.001
Grade
I	Reference
II	1.030	2.80 (2.33–3.37)	<0.001
III/IV	1.980	7.25 (6.07–8.66)	<0.001
ER status
Negative	Reference
Positive	−1.107	0.33 (0.20–0.37)	<0.001
PR status
Negative	Reference
Positive	−0.969	0.38 (0.35–0.42)	<0.001
T stage
T1	Reference
T2	1.383	3.99 (3.59–4.43)	<0.001
T3	2.130	8.41 (7.14–9.91)	<0.001
T4	2.506	12.30 (10.20–14.70)	<0.001
N stage
N0	Reference
N1	1.245	3.47 (3.11–3.88)	<0.001
N2	1.472	4.36 (3.83–4.96)	<0.001
N3	1.589	4.90 (4.30–5.58)	<0.001
Surgery
BCS	Reference
Mastectomy	1.035	2.81 (2.56–3.1)	<0.001
IDC – infiltrating ductal carcinoma; ILC – infiltrating lobular carcinoma; ER – estrogen receptor; PR – progesterone receptor; BCS – breast-conserving surgery; BCSD – breast cancer-specific death; OCSD – other cause-specific death; HR – subdistribution hazard ratio; CI – confidence interval; T – tumor stage; N – nearby lymph node stage. ^* Including American Indian/Alaskan native and Pacific Islander; ^** including other histology of invasive breast cancer except IDC and ILC.

Back to the Article