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17 September 2020: Database Analysis

Effects of Pulsatile Frequency of Left Ventricular Assist Device (LVAD) on Coronary Perfusion: A Numerical Simulation Study

Yuanfei Zhu 1ABCE , Ming Yang 1AEG* , Yan Zhang 2BCF* , Fan Meng 1DEF , Tianyue Yang 1AC , Zhiwei Fang 1BF

DOI: 10.12659/MSM.925367

Med Sci Monit 2020; 26:e925367

Table 3 Simulated hemodynamic responses of the normal, severe HF, and HF with different modes of LVAD support (TIW – total input work; EEP – energy equivalent pressure).

ParametersUnitsNormalHFLVAD support
Co-pulsation (1: 1)Counter-pulsation (1: 1)Counter-pulsation (2: 1)Counter-pulsation (3: 1)
Pump speedrpm006060120180
Cardiac outputL/min5.43.50000
LVAD flowL/min005.45.45.45.4
Pump stroke volumeml0090904530
Heart ratebpm606060606060
Mean LV pressuremmHg59.638.937.121.515.410.9
Peak LV pressuremmHg124.582.8120.958.932.423.4
Mean aortic pressuremmHg10064.9100100100100
Peak aortic pressuremmHg123.782.1122.0122.4113.8111.5
Coronary artery TIWJ/s0.05180.02280.0530.05700.05730.0583
Coronary artery EEPmmHg100.565.9100.4102.4100.799.8
Mean coronary flowml/min234157239252260266
Mean coronary flow%%10067.1102.1107.7111.1113.7

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750