17 September 2020>: Database Analysis
Effects of Pulsatile Frequency of Left Ventricular Assist Device (LVAD) on Coronary Perfusion: A Numerical Simulation Study
Yuanfei Zhu 1ABCE , Ming Yang 1AEG* , Yan Zhang 2BCF* , Fan Meng 1DEF , Tianyue Yang 1AC , Zhiwei Fang 1BFDOI: 10.12659/MSM.925367
Med Sci Monit 2020; 26:e925367
Table 3 Simulated hemodynamic responses of the normal, severe HF, and HF with different modes of LVAD support (TIW – total input work; EEP – energy equivalent pressure).
Parameters | Units | Normal | HF | LVAD support | |||
---|---|---|---|---|---|---|---|
Co-pulsation (1: 1) | Counter-pulsation (1: 1) | Counter-pulsation (2: 1) | Counter-pulsation (3: 1) | ||||
Pump speed | rpm | 0 | 0 | 60 | 60 | 120 | 180 |
Cardiac output | L/min | 5.4 | 3.5 | 0 | 0 | 0 | 0 |
LVAD flow | L/min | 0 | 0 | 5.4 | 5.4 | 5.4 | 5.4 |
Pump stroke volume | ml | 0 | 0 | 90 | 90 | 45 | 30 |
Heart rate | bpm | 60 | 60 | 60 | 60 | 60 | 60 |
Mean LV pressure | mmHg | 59.6 | 38.9 | 37.1 | 21.5 | 15.4 | 10.9 |
Peak LV pressure | mmHg | 124.5 | 82.8 | 120.9 | 58.9 | 32.4 | 23.4 |
Mean aortic pressure | mmHg | 100 | 64.9 | 100 | 100 | 100 | 100 |
Peak aortic pressure | mmHg | 123.7 | 82.1 | 122.0 | 122.4 | 113.8 | 111.5 |
Coronary artery TIW | J/s | 0.0518 | 0.0228 | 0.053 | 0.0570 | 0.0573 | 0.0583 |
Coronary artery EEP | mmHg | 100.5 | 65.9 | 100.4 | 102.4 | 100.7 | 99.8 |
Mean coronary flow | ml/min | 234 | 157 | 239 | 252 | 260 | 266 |
Mean coronary flow% | % | 100 | 67.1 | 102.1 | 107.7 | 111.1 | 113.7 |