11 August 2020: Lab/In Vitro Research
Regulates the Proliferation and Migration of H9c2 Cells
Hongshu Wang 1BCDEF* , Yong Liu 2BC* , Shen Han 1B , Yunfeng Zi 1B , Yayong Zhang 1B , Ruize Kong 3B , Zu Liu 1B , Zhibin Cai 1B , Chongbin Zhong 4B , Wei Liu 5B , Lifeng Li 4B , Lihong Jiang 3AG*DOI: 10.12659/MSM.925388
Med Sci Monit 2020; 26:e925388
Table 7 The expression level of the differentially expressed miRNAs.
| miRNA name | Up/down | Knock-down group | Control group | Fold change | P-value |
|---|---|---|---|---|---|
| rno-let-7c-5p | Up | 48915.11106 | 30241.59174 | 1.617478057 | 0.000585036 |
| rno-miR-148b-3p | Up | 13050.37614 | 8878.710132 | 1.469850456 | 0.004440698 |
| rno-miR-34c-5p | Up | 78966.93058 | 57614.25952 | 1.370614345 | 0.012571048 |
| rno-let-7a-5p | Up | 47559.38952 | 34788.86768 | 1.367086447 | 0.00358211 |
| rno-miR-25-3p | Up | 57776.68845 | 42623.04547 | 1.355526988 | 0.033953322 |
| rno-miR-152-3p | Up | 42183.6253 | 31396.35416 | 1.34358356 | 0.022837988 |
| rno-miR-28-3p | Up | 30385.28687 | 22978.91272 | 1.322311775 | 0.02820609 |
| rno-let-7g-5p | Up | 34278.14567 | 27082.60381 | 1.265688702 | 0.046242269 |
| rno-let-7b-5p | Up | 124070.9522 | 103767.0116 | 1.195668549 | 0.046844482 |
| rno-let-7c-5p | Up | 48915.11106 | 30241.59174 | 1.617478057 | 0.000585036 |
| rno-miR-361-3p | Down | 7844.3994 | 10147.88957 | 0.773007958 | 0.032547771 |
| rno-miR-149-5p | Down | 35717.84765 | 51835.03885 | 0.689067635 | 0.007257529 |
| rno-miR-501-3p | Down | 8354.323719 | 12609.30375 | 0.662552341 | 0.023377351 |
| rno-miR-423-3p | Down | 45506.30495 | 73698.63424 | 0.617464698 | 0.004694093 |
| rno-miR-455-3p | Down | 22803.13515 | 38129.14689 | 0.59804997 | 0.000814365 |
| rno-let-7d-3p | Down | 74365.97971 | 124461.4958 | 0.597501896 | 0.000455668 |
| rno-miR-328a-3p | Down | 15499.58264 | 28493.79288 | 0.543963477 | 0.001862949 |
| rno-miR-296-5p | Down | 6382.826735 | 12088.66725 | 0.528000863 | 0.004167743 |
| rno-miR-484 | Down | 4410.345009 | 8941.350383 | 0.493252677 | 0.019675131 |
| rno-miR-486 | Down | 17019.31937 | 55793.9353 | 0.305038877 | 0.000505176 |
| rno-miR-1-3p | Down | 56.20631293 | 64.31886677 | 0.873869764 | 0.049593776 |