23 June 2020 : Laboratory Research
A PD-L1 Aptamer Selected by Loss-Gain Cell-SELEX Conjugated with Paclitaxel for Treating Triple-Negative Breast Cancer
Xiaoqiu Wu123BEF, Fangfei Li123AG, Yongshu Li1BF, Yuanyuan Yu13DF, Chao Liang13C, Baoting Zhang4DE, Chuanzong Zhao56B, Aiping Lu12378AG, Ge Zhang123AG*DOI: 10.12659/MSM.925583
Med Sci Monit 2020; 26:e925583
Table 1 Sequence of aptamers with the highest rating from each group.
| Name | Sequence (5′-3′) |
|---|---|
| XQ-P1 | ACCGACCGTGCTGGACTCATCGAGATCGGAACACAAGGCCAAATACTATGAGCGAGCCTGGCG |
| XQ-P2 | ACCGACCGTGCTGGACTCACCTACAGGAAGTATCTGTAGATCTCACTATGAGCGAGCCTGGCG |
| XQ-P3 | ACCGACCGTGCTGGACTCATCTCGCTTTTTTCACGGTCCACACTACTATGAGCGAGCCTGGCG |
| XQ-P4 | ACCGACCGTGCTGGACTCACCTACTGGAAGTATCTGTAGATCTCACTATGAGCGAGCCTGGCG |
| XQ-P5 | ACCGACCGTGCTGGACTCAGACCCTGTAGCTACCAAGTCGATCAACTATGAGCGAGCCTGGCG |
| XQ-P6 | ACCGACCGTGCTGGACTCACCTGTTGGAAGTGTCTGTAGACCTCACTATGAGCGAGCCTGGCG |