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10 August 2020 : Clinical Research  

Abnormal Fractional Amplitude of Low-Frequency Fluctuation Changes in Patients with Monocular Blindness: A Functional Magnetic Resonance Imaging (MRI) Study

Jian-Wen Fang1ACDEF, Ya-Jie Yu1ACD, Li-Ying Tang23CD, Si-Yi Chen1C, Meng-Yao Zhang1F, Tie Sun1AF, Shi-Nan Wu1B, Kang Yu1B, Biao Li1B, Yi Shao1ACDG*

DOI: 10.12659/MSM.926224

Med Sci Monit 2020; 26:e926224

Table 5 Brain regions alternation and its potential impact.

Brain regionsExperimental resultBrain functionAnticipated results
Anterior cingulate cortexMB Movement, affect and social behaviorsBehavioral disorders, depression, schizophrenia, and autism
Paracingulate cortexMB Cognitive and affective regulationBipolar disorder
Inferior parietal, but supramarginal and angular gyriMB >HCsPart of the default model network and higher cognitive functionsDepression, anxiety, alexia and agraphia
PrecuneusMB >HCsVisuospatial imagery, episodic memory retrieval, and consciousnessDepression, anxiety and impaired consciousness
MB – monocular blindness; HCs – healthy controls.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750