A Retrospective Study of the C-Reactive Protein to Lymphocyte Ratio and Disease Severity in 108 Patients with Early COVID-19 Pneumonia from January to March 2020 in Wuhan, China

11 September 2020: Clinical Research

Miao Yang ^1ACDEG , Xiaoping Chen ^2ABCF* , Yancheng Xu ^1ADFG*

DOI: 10.12659/MSM.926393

Med Sci Monit 2020; 26:e926393

Table 3 Characteristics of ROC curves in severe COVID-19 patients.

Variables	AUC	SE	95%CI	Youden index J	Associated criterion	Sensitivity	Specificity	P-value
CRP (mg/L)	0.787	0.047	0.698 to 0.860	0.512	>26.30	83.33%	67.86%
LYM (×10/L)	0.643	0.068	0.545 to 0.733	0.327	≤0.90	79.17%	53.57%	0.0347
CRP/LYM (mg·10)	0.782	0.047	0.693 to 0.856	0.518	>16.62	95.83%	55.95%
CRP – C-reactive protein; LYM, lymphocytes; CRP/LYM – the ratio of C-reactive protein to lymphocytes; AUC – areas under the curve; 95% CI – 95% confidence interval; SE – standard error.