12 December 2020: Clinical Research
Comparison of Role of Hand and Wrist Ultrasound in Diagnosis of Subclinical Synovitis in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Retrospective, Single-Center Study
Honghu Tang BCDEF , Yi Liu ABCDEFG , Yi Liu BCDF* , Hua Zhao BCDFDOI: 10.12659/MSM.926436
Med Sci Monit 2020; 26:e926436
Table 1 Demographic and clinical characteristics for 41 patients with SLE and 20 patients with RA involved in this study. We assessed the disease course and joint involvement, laboratory indexes (ANA titer, ENA spectrum, ESR, CRP and IL-6, C3, C4, RF, CCP) and scoring data (DAS28 score, SLEDAI score and ultrasonic score).
| Characteristics | SLE | RA |
|---|---|---|
| Gender (Male/Female) | 5/36 | 5/15 |
| Age (mean±SD) | 34.73±12.30 | 41.10±11.55 |
| Course of disease (mean±SD) | 48.17±48.30 | 21.750±20.89 |
| Joint involvement (n,%) | 26 (63.4) | 20 (100.0) |
| ANA (n, %) | 41 (100.0) | – |
| dsDNA (n, %) | 26 (63.4) | – |
| SSA (n, %) | 31 (75.6) | – |
| SSB (n, %) | 3 (7.3) | – |
| RNP (n, %) | 31 (75.6) | – |
| SM (n, %) | 12 (29.3) | – |
| RIB (n, %) | 11 (26.8) | – |
| C3 (mean±SD) | 0.5301±0.2578 | – |
| C4 (mean±SD) | 0.1262±0.0919 | – |
| RF (mean±SD) | – | 146.35±130.33 |
| CCP (mean±SD) | – | 255.1±189.86 |
| IL-6 (mean±SD) | 9.67±8.63 | 12.7025±8.09 |
| ESR (mean±SD) | 31.37±19.87 | 58.65±38.54 |
| CRP (mean±SD) | 4.9759±4.88 | 26.30±22.29 |
| DAS28 (mean±SD) | 3.3049±0.80 | 5.188±1.13 |
| SLEDAI score (mean±SD) | 12.90±5.54 | – |
| Ultrasonic score (mean±SD) | 11.02±7.171 | 31.10±14.071 |
| SLE – systemic lupus erythematosus; RA – rheumatoid arthritis; ANA – antinuclear antibody; ENA – extractable nuclear antibody; dsDNA – double-strands DNA; SSA – Sjögren syndrome A; SSB – Sjögren syndrome B; RNP – ribonucleoprotein; SM – Smith; RIB – ribosomal; C3 – complement 3; C4 – complement 4; RF – rheumatoid factor; CCP – cyclic citrullinated peptide; AKA – keratin antibody; ESR – erythrocyte sedimentation rate; CRP – C-reactive protein; IL-6 – interleukin-6; SLEDAI – SLE disease activity index; DAS28 – disease activity score-28; SD – standard deviation. | ||