12 December 2020: Clinical Research
Comparison of Role of Hand and Wrist Ultrasound in Diagnosis of Subclinical Synovitis in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Retrospective, Single-Center Study
Honghu Tang BCDEF , Yi Liu ABCDEFG , Yi Liu BCDF* , Hua Zhao BCDFDOI: 10.12659/MSM.926436
Med Sci Monit 2020; 26:e926436
Table 3 Comparative analysis of patients with SLE with and without arthralgia. The results showed that patients with SLE without arthralgia tended to demonstrate abnormality according to the musculoskeletal ultrasound, which suggests that musculoskeletal ultrasound is more sensitive for evaluating SLE arthritis.
| SLE (without arthralgia) | SLE (with arthralgia) | p Values | |
|---|---|---|---|
| Cases (n%) | 15 (36.6%) | 26 (63.4%) | – |
| Age (mean±SD) | 32.00±7.865 | 36.31±14.153 | 0.218 |
| Course of disease | 43.53±36.804 | 50.85±54.345 | 0.646 |
| C3 (mean±SD) | 0.558±0.240 | 0.514±0.271 | 0.607 |
| C4 (mean±SD) | 0.132±0.065 | 0.123±0.106 | 0.773 |
| ANA (mean±SD) | 2.17±0.994 | 2.37±1.091 | 0.566 |
| dsDNA (mean±SD) | 1.20±1.521 | 1.81±1.919 | 0.301 |
| RNP (mean±SD) | 1.20±0.996 | 0.79±0.851 | 0.169 |
| SSA (mean±SD) | 1.52±1.246 | 1.29±0.940 | 0.480 |
| SSB (mean±SD) | 0.27±0.799 | 0.04±0.196 | 0.170 |
| RIB (mean±SD) | 0.33±0.816 | 0.54±0.948 | 0.488 |
| SM (mean±SD) | 0.60±0.737 | 0.21±0.493 | 0.050 |
| ESR (mean±SD) | 19.00±16.353 | 38.50±18.364 | 0.002 |
| CRP (mean±SD) | 2.681±1.512 | 6.300±5.641 | 0.020 |
| IL-6 (mean±SD) | 8.169±7.871 | 10.536±9.069 | 0.404 |
| SLEDAI scores (mean±SD) | 10.07±5.271 | 14.54±5.101 | 0.011 |
| DAS28 scores (mean±SD) | 2.99±0.0.773 | 3.49±0.774 | 0.055 |
| Ultrasonic scores (mean±SD) | 10.67±6.411 | 11.23±7.691 | 0.812 |
| SLE – systemic lupus erythematosus; ANA – antinuclear antibody; ENA – extractable nuclear antibody; dsDNA – double-stranded DNA; SSA – Sjögren syndrome A; SSB – Sjögren syndrome B; RNP – ribonucleoprotein; SM – Smith; RIB – ribosomal; C3 – complement 3; C4 – complement 4; RF – rheumatoid factor; CCP – cyclic citrullinated peptide; AKA – keratin antibody; ESR – erythrocyte sedimentation rate; CRP – C-reactive protein; IL-6 - interleukin-6; SLEDAI – SLE disease activity index; SD – standard deviation. | |||