12 December 2020: Clinical Research
Comparison of Role of Hand and Wrist Ultrasound in Diagnosis of Subclinical Synovitis in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Retrospective, Single-Center Study
Honghu Tang BCDEF , Yi Liu ABCDEFG , Yi Liu BCDF* , Hua Zhao BCDFDOI: 10.12659/MSM.926436
Med Sci Monit 2020; 26:e926436
Table 5 Correlation analysis between musculoskeletal ultrasound scores and inflammatory indexes/autoantibodies. There were positive correlations between RF/CCP antibody titer and ultrasound scores in patients with RA. There were significant correlations between dsDNA titer/RNP autoantibodies and ultrasound scores in patients with SLE. DAS28 score was positively correlated with ultrasound score in patients with RA and in patients with SLE.
| Parameters | Ultrasonic scores | |
|---|---|---|
| r | p Values | |
| ESR | ||
| RA-ESR | 0.932 | 0.000 |
| SLE-ESR | 0.215 | 0.117 |
| CRP | ||
| RA-CRP | 0.906 | 0.000 |
| SLE-CRP | 0.124 | 0.439 |
| Autoantibody | ||
| RA-FR factor | 0.776 | 0.000 |
| RA-CCP | 0.682 | 0.000 |
| SLE-ANA | 0.101 | 0.53 |
| SLE-dsDNA | 0.384 | 0.013 |
| SLE-SSA | −0.079 | 0.622 |
| SLE-SSB | 0.085 | 0.599 |
| SLE-RNP | 0.366 | 0.019 |
| SLE-SM | −0.023 | 0.885 |
| SLE-RIB | −0.024 | 0.882 |
| SLE-C3 | −0.284 | 0.072 |
| SLE-C4 | −0.180 | 0.259 |
| DAS28 | ||
| RA-DAS28 | 0.591 | 0.000 |
| SLE-DAS28 | 0.905 | 0.000 |
| SLEDAI | ||
| SLE-SLEDAI | 0.161 | 0.314 |
| SLE – systemic lupus erythematosus; RA – rheumatoid arthritis; ANA – antinuclear antibody; dsDNA – double-stranded DNA; SSA – Sjögren syndrome A; SSB – Sjögren syndrome B; RNP – ribonucleoprotein; SM – Smith; RIB – ribosomal; C3 – complement 3; C4 – complement 4; RF – rheumatoid factor; CCP – cyclic citrullinated peptide; AKA – keratin antibody; ESR – erythrocyte sedimentation rate; CRP – C-reactive protein; IL-6 – interleukin-6; SLEDAI – SLE disease activity index; DAS28 – disease activity score-28. | ||