25 November 2020 : Clinical Research
Urinary Metabonomic Profiling Discriminates Between Children with Autism and Their Healthy Siblings
Yujie Liang12AE, Zhou Xiao1B, Xiaoyin Ke1F, Paul Yao1E, Yangxia Chen1B, Ling Lin12F, Jianping Lu12AG*DOI: 10.12659/MSM.926634
Med Sci Monit 2020; 26:e926634
Table 2 Summary of the discriminant metabolites accountable for the separation of metabolic profiles between control vs. ASD groups.
| Metabolites | P-value | r | VIP |
|---|---|---|---|
| Butyrate: 1.55(mc), 2.19(m) | 3.150×10 | −0.580 | 3.337 |
| Tryptophan: 4.04(s),3.47(m) | 4.586×10 | 0.513 | 1.708 |
| Citrate: 2.55(d), 2.68(d) | 2.066×10 | −0.650 | 4.072 |
| Creatine: 3.04(s), 3.93(s) | 5.166×10 | 0.612 | 9.475 |
| Lactate: 1.34(d), 4.11(q) | 2.066×10 | −0.656 | 1.502 |
| Pantothenate: 0.88(s), 0.93(s), 7.98(s) | 2.066×10 | −0.569 | 1.245 |
| Serotonin: 6.87(d), 7.13(d), 7.32(s) | 9.015×10 | 0.553 | 1.558 |
| Taurine: 3.27(t), 3.44(t) | 2.176×10 | 0.552 | 5.006 |
| Trigonelline: 4.44(s), 8.01(m), 8.84(t), 9.13(s) | 2.589×10 | −0.575 | 1.183 |
| Melatonin: 3.84(s), 1.92(s) | 8.418×10 | −0.545 | 2.072 |






