25 October 2020: Database Analysis
Expression and Prognostic Analyses of ITGA3, ITGA5, and ITGA6 in Head and Neck Squamous Cell Carcinoma
Chen Feng 12ABCDEF , Xiaoxue Jin 12ABCD , Yingying Han 12ABCD , Ruixiang Guo 12ABC , Juanjuan Zou 12CDF , Yanzhong Li 12DEFG , Yan Wang 12DEFG*DOI: 10.12659/MSM.926800
Med Sci Monit 2020; 26:e926800
Table 1 Comparison of expression levels of ITGA3, ITGA5, and ITGA6 between head and neck squamous cell carcinoma (HNSC) and normal samples in ONCOMINE database.
| Gene ID | Types of HNSC vs. normal | Fold change | P value | t-Test | References |
|---|---|---|---|---|---|
| ITGA3 | Tongue squamous cell carcinoma normal | 3.789 | 2.94E-12 | 8.728 | Estilo et al., 2009 |
| Head and neck squamous cell carcinoma normal | 2.207 | 3.61E-8 | 6.437 | Ginos et al., 2004 | |
| Oral cavity squamous cell carcinoma normal | 3.147 | 3.88E-24 | 14.600 | Peng et al., 2011 | |
| Tongue carcinoma normal | 2.299 | 1.01E-5 | 5.745 | Pyeon et al., 2007 | |
| Tongue squamous cell carcinoma normal | 2.068 | 8.82E-10 | 7.310 | Talbot et al., 2005 | |
| ITGA5 | Tongue squamous cell carcinoma normal | 3.027 | 9.33E-7 | 5.339 | Estilo et al., 2009 |
| Head and neck squamous cell carcinoma normal | 2.307 | 1.37E-7 | 6.676 | Ginos et al., 2004 | |
| Oral cavity squamous cell carcinoma normal | 2.761 | 3.26E-18 | 11.351 | Peng et al., 2011 | |
| ITGA6 | Tongue squamous cell carcinoma normal | 6.290 | 2.30E-11 | 8.313 | Estilo et al., 2009 |
| Oropharyngeal carcinoma normal | 2.757 | 1.94E-5 | 5.944 | Pyeon et al., 2007 | |
| Tongue carcinoma normal | 3.133 | 1.81E-7 | 6.469 | Pyeon et al., 2007 | |
| Tongue squamous cell carcinoma normal | 4.086 | 5.58E-12 | 9.438 | Talbot et al., 2005 | |
| Tongue squamous cell carcinoma normal | 2.958 | 1.67E-7 | 6.534 | Ye et al., 2008 |