25 October 2020: Database Analysis
Expression and Prognostic Analyses of ITGA3, ITGA5, and ITGA6 in Head and Neck Squamous Cell Carcinoma
Chen Feng 12ABCDEF , Xiaoxue Jin 12ABCD , Yingying Han 12ABCD , Ruixiang Guo 12ABC , Juanjuan Zou 12CDF , Yanzhong Li 12DEFG , Yan Wang 12DEFG*DOI: 10.12659/MSM.926800
Med Sci Monit 2020; 26:e926800
Table 5 Univariate and multivariate Cox analysis of overall survival in head and neck squamous cell carcinoma (HNSC).
| Characteristics | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | X95.CI | p | HR | X95.CI | P | |
| Age: >65 ≤65 | 1.337 | 1.009–1.771 | 1.315 | 0.984–1.758 | 0.064 | |
| Gender: Male Female | 0.720 | 0.537–0.965 | 0.788 | 0.582–1.067 | 0.123 | |
| Clinical stage: III/IV I/II | 1.139 | 0.814–1.592 | 0.447 | |||
| Histological grade: G3/G4 G1/G2 | 0.931 | 0.685–1.264 | 0.646 | |||
| ITGA3 expression: High low | 1.332 | 1.010–1.758 | 1.046 | 0.757–1.446 | 0.784 | |
| ITGA5 expression: High low | 1.464 | 1.108–1.935 | 1.347 | 0.988–1.837 | ||
| ITGA6 expression: High low | 1.353 | 1.026–1.784 | 1.202 | 0.871–1.658 | 0.264 | |