Identification of the Prognostic Value and Clinical Significance of Interferon Regulatory Factors (IRFs) in Colon Adenocarcinoma

Munire Yuemaier; Zhiqiang Zhou; Youxu Zhou; Chengwen Wu; Fei Li; Xiaodan Liang; Haihan Kang; Dongfang Shen; Fei Gao; Jinxi Lin

doi:10.12659/MSM.927073

08 November 2020 : Database Analysis

Identification of the Prognostic Value and Clinical Significance of Interferon Regulatory Factors (IRFs) in Colon Adenocarcinoma

Munire Yuemaier^1ABCDEF, Zhiqiang Zhou^1AEFG*, Youxu Zhou^2ABCDE, Chengwen Wu^1CDE, Fei Li^1CDEF, Xiaodan Liang^1BCEF, Haihan Kang^1BCDEF, Dongfang Shen^1FG, Fei Gao^1EFG, Jinxi Lin^2E

DOI: 10.12659/MSM.927073

Med Sci Monit 2020; 26:e927073

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Table 6 miRNA target networks of the IRF family in COAD.

IRFs	Enriched miRNA target	Leading edge num	P value
IRF1	GTATTAT, MIR-369-3p	42	0
IRF1	CTTGTA, MIR-381	44	0
IRF2	GTGTTGA, MIR-505	25	0
IRF2	GCACCTT, MIR-18A, MIR-18B	44	0
IRF3	GCACTTT, MIR-17-5P,MIR-20A, MIR-106A, MIR-106BMIR-20B, MIR519D	229	0
IRF3	TGTATGA, MIR-485-3P	63	0
IRF4	CAGTATT, MIR-200B, MIR-200C, MIR-429	166	0.042
IRF4	ACTGTGA, MIR-27A, MIR-27B	152	0.060
IRF5	ATGCTGC, MIR-103, MIR-107	67	0.002
IRF5	TCCAGAG, MIR-518C	46	0.002
IRF6	GACAATC, MIR-219	53	0
IRF6	GCACTTT, MIR-17-5P, MIR-20A, MIR-106A, MIR-106B, MIR-20B, MIR-519D	203	0
IRF7	CCAGGGG, MIR-331	21	0
IRF7	CAGTCAC, MIR-134	17	0
IRF8	CACTTTG, MIR-520G, MIR-520H	43	0
IRF8	AAGCAAT, MIR-137	57	0
IRF9	CCAGGTT, MIR-490	21	0
IRF9	TATCTGG, MIR-488	16	0

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Identification of the Prognostic Value and Clinical Significance of Interferon Regulatory Factors (IRFs) in Colon Adenocarcinoma

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