09 December 2020 : Database Analysis
Identification of a 6-Gene Signature Associated with Resistance to Tyrosine Kinase Inhibitors: Prognosis for Clear Cell Renal Cell Carcinoma
Qinke Li1ABCE, Wenbo Yang1CD, Maoqing Lu1DF, Ronggui Zhang1AG*DOI: 10.12659/MSM.927078
Med Sci Monit 2020; 26:e927078
Table 1 Clinical characteristics of patients with clear cell renal cell carcinoma in entire cohort, training cohort, and validation cohort.
| Entire cohort | Train cohort | Validation cohort | |
|---|---|---|---|
| Total risk | 463 | 232 | 231 |
| High | 225 | 116 | 109 |
| Low | 238 | 116 | 122 |
| Survival status | |||
| Living | 326 | 162 | 164 |
| Deceased | 137 | 70 | 67 |
| Age | |||
| <60 | 227 | 111 | 116 |
| ≥60 | 236 | 121 | 115 |
| Gender | |||
| Female | 163 | 75 | 88 |
| Male | 300 | 157 | 143 |
| Grade | |||
| G1 | 10 | 6 | 4 |
| G2 | 204 | 100 | 104 |
| G3 | 180 | 94 | 86 |
| G4 | 63 | 29 | 34 |
| GX | 4 | 2 | 2 |
| Unknown | 2 | 1 | 1 |
| Stage | |||
| Stage I | 232 | 117 | 115 |
| Stage II | 53 | 26 | 27 |
| Stage III | 105 | 51 | 54 |
| Stage IV | 70 | 37 | 33 |
| Unknown | 3 | 1 | 2 |
| T stage | |||
| T1 | 237 | 120 | 117 |
| T2 | 64 | 32 | 32 |
| T3 | 153 | 79 | 74 |
| T4 | 9 | 1 | 8 |
| M stage | |||
| M0 | 370 | 186 | 184 |
| M1 | 67 | 38 | 29 |
| MX | 24 | 7 | 17 |
| Unknown | 2 | 1 | 1 |
| N stage | |||
| N0 | 208 | 103 | 105 |
| N1 | 13 | 5 | 8 |
| NX | 242 | 124 | 118 |






